Enablex and Roxicet drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Roxicet (acetaminophen; oxycodone hydrochloride). Common drug interactions include arthralgia among females.
The phase IV clinical study analyzes what interactions people have when they take Enablex and Roxicet. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Enablex?
Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.
What is Roxicet?
Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.
12 people who take Enablex and Roxicet together, and have interactions are studied.

What are the common drug interactions of Enablex and Roxicet, by gender? *:
female:
- Arthralgia (joint pain)
- Back pain
- Cardiac failure congestive
- Cystitis noninfective (non-infectious inflammation of the wall of the bladder)
- Dental caries
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dizziness
- Drug ineffective
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Facial pain
male:
n/a
What are the common drug interactions of Enablex and Roxicet, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Arthralgia (joint pain)
- Back pain
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Dependence
- Drug abuse
- Drug ineffective
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Eating disorder
- Fall
50-59:
n/a
60+:
- Renal failure (kidney dysfunction)
- Anaemia (lack of blood)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dizziness
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Facial pain
- Fall
- Groin pain
- Haematuria (presence of blood in urine)
- Infection
What are the existing conditions these people have? *
- Urinary Tract Infection: 6 people, 50.00%
- Insomnia (sleeplessness): 6 people, 50.00%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 50.00%
- High Blood Pressure: 6 people, 50.00%
- Muscle Spasms (muscle contraction): 6 people, 50.00%
- Depression: 5 people, 41.67%
- Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 41.67%
- Hypertriglyceridaemia (excess of triglycerides in the blood): 5 people, 41.67%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 5 people, 41.67%
- Allergic Rhinitis: 5 people, 41.67%
* Approximation only. Some reports may have incomplete information.
Do you take Enablex and Roxicet?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Enablex and Roxicet:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enablex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Roxicet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enablex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Roxicet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on darifenacin hydrobromide and acetaminophen; oxycodone hydrochloride (the active ingredients of Enablex and Roxicet, respectively), and Enablex and Roxicet (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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