Enablex and Xopenex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Xopenex (levalbuterol hydrochloride). Common drug interactions include sinusitis among females and tinea pedis among males.
The phase IV clinical study analyzes what interactions people have when they take Enablex and Xopenex. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Enablex?
Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.
What is Xopenex?
Xopenex has active ingredients of levalbuterol hydrochloride. It is often used in asthma. eHealthMe is studying from 13,816 Xopenex users. Check the latest studies of Xopenex.
29 people who take Enablex and Xopenex together, and have interactions are studied.

What are the common drug interactions of Enablex and Xopenex, by gender? *:
female:
- Sinusitis (inflammation of sinus)
- Thrombosis (formation of a blood clot inside a blood vessel)
- Aphasia (damage to the parts of the brain that control language)
- Chronic kidney disease
- Deafness
- Depressed level of consciousness
- Dysarthria (speech disorder)
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
- Hepatic failure (liver failure)
male:
- Tinea pedis (a contagious skin infection caused by the ringworm fungus)
- Abasia (inability to walk)
- Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
- Cardiac disorder
- Cardiac failure congestive
- Cardioversion
- Death
- Pneumonia
- Respiratory disorder (respiratory disease)
- Arthralgia (joint pain)
What are the common drug interactions of Enablex and Xopenex, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Abasia (inability to walk)
- Arthralgia (joint pain)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Femur fracture
- Pain in extremity
- Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
- Cardiac disorder
10-19:
n/a
20-29:
n/a
30-39:
- Thrombosis (formation of a blood clot inside a blood vessel)
- Hepatic failure (liver failure)
- Abdominal pain
- Fear
- Haematemesis (vomiting of blood)
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Pneumonia
- Pyrexia (fever)
- Abasia (inability to walk)
40-49:
- Depression
- Muscle spasms (muscle contraction)
50-59:
n/a
60+:
- Dyspnoea (difficult or laboured respiration)
- Aphasia (damage to the parts of the brain that control language)
- Blood creatinine increased
- Blood urea increased
- Cardiac failure congestive
- Cardioversion
- Coagulopathy (blood's ability to clot is impaired)
- Colitis (inflammation of colon)
- Contusion (a type of hematoma of tissue in which capillaries)
- Cough
What are the existing conditions these people have? *
- Obstructive Airways Disorder (a progressive disease that makes it hard to breathe): 6 people, 20.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 20.69%
- Allergic Rhinitis: 5 people, 17.24%
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine): 3 people, 10.34%
- Diabetes: 3 people, 10.34%
- Depression: 3 people, 10.34%
- Constipation: 3 people, 10.34%
- Nausea (feeling of having an urge to vomit): 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Enablex and Xopenex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Enablex and Xopenex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Enablex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Xopenex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Enablex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Xopenex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on darifenacin hydrobromide and levalbuterol hydrochloride (the active ingredients of Enablex and Xopenex, respectively), and Enablex and Xopenex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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