Enbrel and Cataflam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enbrel (etanercept) and Cataflam (diclofenac potassium). Common drug interactions include pruritus among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Enbrel and Cataflam. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Cataflam?

Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.

On Jul, 21, 2026

56 people who take Enbrel and Cataflam together, and have interactions are studied.

What are the common drug interactions of Enbrel and Cataflam, by gender? *:

female:

Pruritus (severe itching of the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Pustular psoriasis (raised bumps on the skin that are filled with pus)
Rash macular (small, flat red spots)
Skin discolouration (change of skin colour)
Tooth loss
Wound infection
Abdominal discomfort
Abdominal pain
Alopecia (absence of hair from areas of the body)

male:

Drug ineffective
Spinal osteoarthritis (joint cartilage loss in spine)
Pain in extremity
Walking disability
Diarrhoea
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Psoriasis (immune-mediated disease that affects the skin)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Urinary tract infection
Dysentery (infection of the intestines resulting in severe diarrhoea with the presence of blood and mucus in the faeces)

What are the common drug interactions of Enbrel and Cataflam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Dermatitis allergic (inflammation of the skin due allergic reaction)
Sensation of foreign body

20-29:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Psoriasis (immune-mediated disease that affects the skin)

30-39:

Brain stem infarction (brainstem stroke)
Hypertension (high blood pressure)
Tuberculin test positive
Dyspnoea (difficult or laboured respiration)
Escherichia infection (bacterial infection by escherichia coli)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nephritis (inflammation of the nephrons in the kidneys)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Corneal infection (corneal infection)
Meningeal disorder (disease of meninges)

40-49:

Arthralgia (joint pain)
Arthropathy
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Discomfort
Ear infection
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Hepatic enzyme increased
Hypersensitivity
Influenza
Injection site rash

50-59:

Dyslipidaemia (abnormal amount of lipids)
Spinal osteoarthritis (joint cartilage loss in spine)
Spinal pain (pain in spine)
Arthralgia (joint pain)
Drug ineffective
Fatigue (feeling of tiredness)
Dementia alzheimer's type (loss of mental ability with alzheimer's symptom)
Hypersensitivity
Inflammation
Injection site erythema (redness at injection site)

60+:

Drug ineffective
Arthralgia (joint pain)
Inflammation
Therapeutic response decreased (less preventive response)
Activities of daily living impaired
Asthenia (weakness)
Decreased immune responsiveness
Depressed mood
Erythema (redness of the skin)
Eye disorder

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 10.71%
Ankylosing Spondylitis (type of arthritis affecting the spine): 6 people, 10.71%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.36%

* Approximation only. Some reports may have incomplete information.

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