Enbrel and Msm drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enbrel (etanercept) and Msm (methylsulfonylmethane). Common drug interactions include anaemia among females and fungal infection among males.

The phase IV clinical study analyzes what interactions people have when they take Enbrel and Msm. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

What is Msm?

Msm has active ingredients of methylsulfonylmethane. It is often used in joint pain. eHealthMe is studying from 1,210 Msm users. Check the latest studies of Msm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

36 people who take Enbrel and Msm together, and have interactions are studied.

What are the common drug interactions of Enbrel and Msm, by gender? *:

female:

Anaemia (lack of blood)
Eye irritation
Eye pain
Kidney infection
Peripheral swelling
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)
Pain
Adverse drug reaction
Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

Fungal infection
Injection site reaction
Joint swelling
Localised infection (infection at the single location)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Stomatitis (inflammation of mucous membrane of mouth)

What are the common drug interactions of Enbrel and Msm, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Pain in extremity
Psoriasis (immune-mediated disease that affects the skin)
Tendon pain
Therapeutic response decreased (less preventive response)

40-49:

Infection
Anaemia (lack of blood)
Drug ineffective
Eye irritation
Eye pain
Kidney infection
Pain
Peripheral swelling
Pulmonary embolism (blockage of the main artery of the lung)
Thrombosis (formation of a blood clot inside a blood vessel)

50-59:

Joint swelling
Anaemia (lack of blood)
Blood cholesterol increased
Chills (felling of cold)
Cough
Dizziness
Drug ineffective
Eye irritation
Eye pain
Fungal infection

60+:

Arthritis (form of joint disorder that involves inflammation of one or more joints)
Cartilage injury
Diarrhoea
Flatulence (flatus expelled through the anus)
Injection site erythema (redness at injection site)
Injection site mass
Injection site swelling
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Tongue neoplasm (tumour of tongue)
Injection site urticaria (rash of round, red welts on the skin at injection site)

What are the existing conditions these people have? *

Pain: 3 people, 8.33%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 8.33%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.56%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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