Entocort ec and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entocort ec (budesonide) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include nausea among females and gastritis erosive among males.

The phase IV clinical study analyzes what interactions people have when they take Entocort ec and Spiriva. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Entocort ec?

Entocort ec has active ingredients of budesonide. It is often used in crohn's disease. eHealthMe is studying from 3,232 Entocort ec users. Check the latest studies of Entocort ec.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Aug, 09, 2026

35 people who take Entocort ec and Spiriva together, and have interactions are studied.

Entocort ec and Spiriva drug interactions.

What are the common drug interactions of Entocort Ec and Spiriva, by gender? *:

female:

Nausea (feeling of having an urge to vomit)
Diarrhoea
Rash papular (redness with papule)
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Asthenia (weakness)
Blood glucose increased
Constipation
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
White blood cell count decreased
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Pneumonia
Attention deficit/hyperactivity disorder

What are the common drug interactions of Entocort Ec and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Attention deficit/hyperactivity disorder
Disturbance in attention
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Psychomotor hyperactivity (feelings of extreme restlessness)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

20-29:

n/a

30-39:

n/a

40-49:

Rash papular (redness with papule)
Peripheral embolism (sudden interruption of blood flow to an organ or body part)
Abscess jaw (tooth abscess or root abscess)
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Fatigue (feeling of tiredness)
Influenza like illness
Nausea (feeling of having an urge to vomit)

50-59:

Gastritis (inflammation of stomach)
General physical health deterioration (weak health status)
Intestinal obstruction
Weight decreased
Asthenia (weakness)
Burning sensation
Erythema (redness of the skin)
Local swelling (swelling at the site of some application of substance or injury)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Oxygen saturation decreased

60+:

Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
White blood cell count decreased
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Nausea (feeling of having an urge to vomit)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)

What are the existing conditions these people have? *

High Blood Pressure: 20 people, 57.14%
Insomnia (sleeplessness): 20 people, 57.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 34.29%
Diarrhea: 12 people, 34.29%
Diabetes: 11 people, 31.43%
Enteritis (inflammation of the small intestine): 11 people, 31.43%
Muscle Spasms (muscle contraction): 11 people, 31.43%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 11 people, 31.43%
Hepatic Neoplasm Malignant (liver cancer): 11 people, 31.43%
Ascites (accumulation of fluid in the abdominal cavity): 11 people, 31.43%

* Approximation only. Some reports may have incomplete information.

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