Acarbose and Entresto drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acarbose (acarbose) and Entresto (sacubitril; valsartan). Common drug interactions include hypokalaemia among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Acarbose and Entresto. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Acarbose?

Acarbose has active ingredients of acarbose. It is often used in diabetes. eHealthMe is studying from 4,605 Acarbose users. Check the latest studies of Acarbose.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,626 Entresto users. Check the latest studies of Entresto.

On Jun, 10, 2026

15 people who take Acarbose and Entresto together, and have interactions are studied.

Acarbose and Entresto drug interactions.

What are the common drug interactions of Acarbose and Entresto, by gender? *:

female:

Hypokalaemia (low potassium)
Oedema peripheral (superficial swelling)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Folliculitis (infection of hair root)
Hypertension (high blood pressure)
Hypoproteinaemia (too little prolactin circulating in the blood)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Marasmus (severe malnutrition characterized by energy deficiency)
Urinary tract infection

male:

Abdominal distension
Blood creatinine increased
Peripheral swelling
White blood cell count increased
Blood potassium increased
Decreased appetite
Dizziness postural
Eructation (release of gas from the digestive tract)
Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)

What are the common drug interactions of Acarbose and Entresto, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Blood creatinine increased
Blood potassium increased
Decreased appetite
Dizziness postural
Eructation (release of gas from the digestive tract)
Hypotension (abnormally low blood pressure)
Renal impairment (severely reduced kidney function)
Weight decreased

50-59:

n/a

60+:

Hypokalaemia (low potassium)
Oedema peripheral (superficial swelling)
Weight decreased
Syncope (loss of consciousness with an inability to maintain postural tone)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Acute myocardial infarction (acute heart attack)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Aortic valve incompetence
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Atrioventricular block first degree (heart block first degree)

What are the existing conditions these people have? *

Cardiac Failure: 11 people, 73.33%
Cardiac Failure Chronic: 8 people, 53.33%
Stress And Anxiety: 5 people, 33.33%
Rashes (redness): 5 people, 33.33%
Itching: 5 people, 33.33%
Pre-Existing Disease: 4 people, 26.67%
Type 2 Diabetes: 3 people, 20.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 13.33%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 13.33%
Depression: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

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