Entresto and Aripiprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Aripiprazole (aripiprazole). Common drug interactions include cough among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Aripiprazole. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.

What is Aripiprazole?

Aripiprazole has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 39,143 Aripiprazole users. Check the latest studies of Aripiprazole.

On Jul, 16, 2026

34 people who take Entresto and Aripiprazole together, and have interactions are studied.

Entresto and Aripiprazole drug interactions.

What are the common drug interactions of Entresto and Aripiprazole, by gender? *:

female:

Cough
Creatinine renal clearance decreased
Fatigue (feeling of tiredness)
Glomerular filtration rate decreased
Hyperkeratosis (thickening of the outer layer of the skin)
Lip swelling
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Macule (a discoloured spot on the skin)
Presyncope
Psoriasis (immune-mediated disease that affects the skin)

male:

Dizziness
Syncope (loss of consciousness with an inability to maintain postural tone)
Hallucination, auditory (perceiving sounds without auditory stimulus)
Hypokalaemia (low potassium)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Renal impairment (severely reduced kidney function)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Presyncope
Hyperthyroidism (over activity of the thyroid gland)

What are the common drug interactions of Entresto and Aripiprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Gamma-glutamyltransferase increased
Alanine aminotransferase increased
Blood cholesterol increased
Blood thyroid stimulating hormone increased
Blood triglycerides increased
Blood uric acid increased
Body mass index increased
C-reactive protein increased
Cardiac disorder
Dehydration (dryness resulting from the removal of water)

30-39:

n/a

40-49:

Electrocardiogram qt prolonged
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Blood pressure decreased
Borderline personality disorder
Chest pain
Dry mouth
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fatigue (feeling of tiredness)
Fluid intake restriction
Headache (pain in head)

50-59:

Dyspnoea (difficult or laboured respiration)
Dizziness
Blood creatinine increased
Chest pain
Concussion (short loss of normal brain function in response to a head injury)
Delusion (a false belief or opinion)
Facial bones fracture (bone fracture of face)
Fall
Fatigue (feeling of tiredness)
Hallucination, auditory (perceiving sounds without auditory stimulus)

60+:

Asthenia (weakness)
Blood pressure decreased
Fatigue (feeling of tiredness)
Hypotension (abnormally low blood pressure)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Presyncope
Respiratory failure (inadequate gas exchange by the respiratory system)
Suicide attempt
Urinary tract infection
Dizziness

What are the existing conditions these people have? *

Cardiac Failure: 6 people, 17.65%
Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 4 people, 11.76%
Stress And Anxiety: 4 people, 11.76%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 11.76%
Hyperthyroidism (over activity of the thyroid gland): 4 people, 11.76%
High Blood Pressure: 4 people, 11.76%
Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 3 people, 8.82%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 5.88%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.88%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Entresto and Aripiprazole?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously