Entresto and Timolol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entresto (sacubitril; valsartan) and Timolol (timolol). Common drug interactions include fall among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Entresto and Timolol. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,629 Entresto users. Check the latest studies of Entresto.

What is Timolol?

Timolol has active ingredients of timolol. It is often used in glaucoma. eHealthMe is studying from 9,142 Timolol users. Check the latest studies of Timolol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

30 people who take Entresto and Timolol together, and have interactions are studied.

Entresto and Timolol drug interactions.

What are the common drug interactions of Entresto and Timolol, by gender? *:

female:

  1. Fall
  2. Rib fracture
  3. Soft tissue infection
  4. Anaemia (lack of blood)
  5. Ankle fracture
  6. Blindness
  7. Cardiac disorder
  8. Cardiac failure
  9. Chest pain
  10. Death

male:

  1. Dizziness
  2. Renal impairment (severely reduced kidney function)
  3. Cough
  4. Drug ineffective
  5. Hypoacusis (loss of hearing)
  6. Micturition urgency (urgency to pass the urine)
  7. Oropharyngeal discomfort (pain or irritation of oropharynx)
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  9. Sleep disorder
  10. Weight fluctuation

What are the common drug interactions of Entresto and Timolol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Dizziness
  2. Hypotension (abnormally low blood pressure)
  3. Anxiety
  4. Confusional state
  5. Cough
  6. Drug ineffective
  7. Fluid retention (an abnormal accumulation of fluid in the blood)
  8. Hypoacusis (loss of hearing)
  9. Limb discomfort (discomfort in leg)
  10. Micturition urgency (urgency to pass the urine)

What are the existing conditions these people have? *

  1. Cardiac Failure: 8 people, 26.67%
  2. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 13.33%
  3. Cardiac Failure Congestive: 3 people, 10.00%
  4. Type 2 Diabetes: 2 people, 6.67%
  5. Pain: 2 people, 6.67%
  6. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 6.67%
  7. Multiple Myeloma (cancer of the plasma cells): 2 people, 6.67%
  8. High Blood Pressure: 2 people, 6.67%
  9. Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Entresto and Timolol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Entresto and Timolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Entresto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Timolol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Entresto and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Timolol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on sacubitril; valsartan and timolol (the active ingredients of Entresto and Timolol, respectively), and Entresto and Timolol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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