Entyvio and Chlorthalidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entyvio (vedolizumab) and Chlorthalidone (chlorthalidone). Common drug interactions include breast cancer among females and influenza among males.

The phase IV clinical study analyzes what interactions people have when they take Entyvio and Chlorthalidone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Entyvio?

Entyvio has active ingredients of vedolizumab. It is often used in crohn's disease. eHealthMe is studying from 23,827 Entyvio users. Check the latest studies of Entyvio.

What is Chlorthalidone?

Chlorthalidone has active ingredients of chlorthalidone. It is often used in high blood pressure. eHealthMe is studying from 12,482 Chlorthalidone users. Check the latest studies of Chlorthalidone.



On Aug, 12, 2026

17 people who take Entyvio and Chlorthalidone together, and have interactions are studied.

Entyvio and Chlorthalidone drug interactions.

What are the common drug interactions of Entyvio and Chlorthalidone, by gender? *:

female:

  1. Breast cancer
  2. Diarrhoea
  3. Discomfort
  4. Hidradenitis (chronic disease of a type of sweat gland)
  5. Polyarthritis (arthritis which involves 5 or more joints simultaneously)
  6. Blood immunoglobulin g decreased
  7. Blood immunoglobulin m decreased
  8. Cd4 lymphocytes decreased
  9. Leukopenia (less number of white blood cells in blood)
  10. Lymphopenia (an abnormally low level of lymphocytes in the blood)

male:

  1. Influenza
  2. Influenza like illness
  3. Drug level below therapeutic
  4. Hypersensitivity
  5. Hypotension (abnormally low blood pressure)
  6. Tongue disorder (disease of tongue)
  7. Tooth infection
  8. Waist circumference increased
  9. Nausea (feeling of having an urge to vomit)
  10. Pneumonia

What are the common drug interactions of Entyvio and Chlorthalidone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Breast cancer
  2. Blood immunoglobulin g decreased
  3. Blood immunoglobulin m decreased
  4. Cd4 lymphocytes decreased
  5. Leukopenia (less number of white blood cells in blood)
  6. Lymphopenia (an abnormally low level of lymphocytes in the blood)
  7. Polyarthritis (arthritis which involves 5 or more joints simultaneously)
  8. Toxoplasma serology positive

60+:

  1. Influenza
  2. Influenza like illness
  3. Waist circumference increased
  4. Nausea (feeling of having an urge to vomit)
  5. Pneumonia
  6. White blood cell count decreased
  7. Colitis ulcerative (inflammation of colon with ulcer)
  8. Drug level below therapeutic
  9. Hypotension (abnormally low blood pressure)
  10. Tongue disorder (disease of tongue)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 17.65%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
  3. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 11.76%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 11.76%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 11.76%
  7. High Blood Cholesterol: 1 person, 5.88%
  8. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 5.88%
  9. Cardiac Disorder: 1 person, 5.88%
  10. Colitis (inflammation of colon): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Entyvio and Chlorthalidone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Entyvio and Chlorthalidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Entyvio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Chlorthalidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Entyvio and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chlorthalidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on vedolizumab and chlorthalidone (the active ingredients of Entyvio and Chlorthalidone, respectively), and Entyvio and Chlorthalidone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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