Entyvio and Cosentyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Entyvio (vedolizumab) and Cosentyx (secukinumab). Common drug interactions include drug hypersensitivity among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Entyvio and Cosentyx. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.

What is Entyvio?

Entyvio has active ingredients of vedolizumab. It is often used in crohn's disease. eHealthMe is studying from 23,827 Entyvio users. Check the latest studies of Entyvio.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

On Aug, 05, 2026

92 people who take Entyvio and Cosentyx together, and have interactions are studied.

What are the common drug interactions of Entyvio and Cosentyx, by gender? *:

female:

Drug hypersensitivity
General physical health deterioration (weak health status)
Insomnia (sleeplessness)
Joint dislocation (a joint position is changed from normal position)
Lower limb fracture
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Pyrexia (fever)
Infection
Infusion related reaction

male:

Fatigue (feeling of tiredness)
Psoriasis (immune-mediated disease that affects the skin)
Platelet count decreased
Pruritus (severe itching of the skin)
Pyrexia (fever)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Skin plaque (red, scaly patches to appear on the skin)
White blood cell count decreased
Blood pressure systolic increased
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)

What are the common drug interactions of Entyvio and Cosentyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Confusional state
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Drug ineffective
Pericarditis (inflammation of the pericardium)
Fatigue (feeling of tiredness)
Lower respiratory tract infection
Pain
Hand deformity
Arthralgia (joint pain)
Arthropathy

50-59:

Blood pressure systolic increased
Drug ineffective
Diarrhoea
Headache (pain in head)
Vomiting

60+:

n/a

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 80 people, 86.96%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 79 people, 85.87%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 66 people, 71.74%
Psoriasis (immune-mediated disease that affects the skin): 64 people, 69.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 61 people, 66.30%
Inflammation: 52 people, 56.52%
Pain: 48 people, 52.17%
Fever: 48 people, 52.17%
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder): 48 people, 52.17%
Synovitis (inflammation of the synovial membrane): 45 people, 48.91%

* Approximation only. Some reports may have incomplete information.

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