Enulose and Motrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enulose (lactulose) and Motrin (ibuprofen). Common drug interactions include pulmonary embolism among females and angina pectoris among males.

The phase IV clinical study analyzes what interactions people have when they take Enulose and Motrin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

On Jul, 13, 2026

13 people who take Enulose and Motrin together, and have interactions are studied.

What are the common drug interactions of Enulose and Motrin, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Urinary tract infection bacterial
Dyspnoea (difficult or laboured respiration)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Productive cough
Back pain
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Angina pectoris (chest pain due to ischemia of the heart muscle)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Asthenia (weakness)
Productive cough
Renal disorder (kidney disease)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Unevaluable reaction
Cardiac disorder
Chills (felling of cold)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Enulose and Motrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Infusion related reaction

20-29:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

Back pain
Dyspnoea (difficult or laboured respiration)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anaemia of malignant disease
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arteriosclerosis (thickening and hardening of arteries)

50-59:

n/a

60+:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Dyspnoea (difficult or laboured respiration)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Hypotension (abnormally low blood pressure)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urinary tract infection bacterial
Asthenia (weakness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Loss of consciousness

What are the existing conditions these people have? *

Fever: 5 people, 38.46%
Nausea (feeling of having an urge to vomit): 5 people, 38.46%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 38.46%
Stress And Anxiety: 4 people, 30.77%
Parkinson's Disease: 4 people, 30.77%
Breast Cancer: 4 people, 30.77%
Depression: 4 people, 30.77%
Diabetes: 4 people, 30.77%
Hypersensitivity: 4 people, 30.77%
Metastases To Bone (cancer spreads to bone): 3 people, 23.08%

* Approximation only. Some reports may have incomplete information.

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