Enulose and Sinemet drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enulose (lactulose) and Sinemet (carbidopa; levodopa). Common drug interactions include thyroid disorder among females and blood pressure increased among males.

The phase IV clinical study analyzes what interactions people have when they take Enulose and Sinemet. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Enulose?

Enulose has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 711 Enulose users. Check the latest studies of Enulose.

What is Sinemet?

Sinemet has active ingredients of carbidopa; levodopa. It is often used in parkinson's disease. eHealthMe is studying from 29,601 Sinemet users. Check the latest studies of Sinemet.

On Jul, 07, 2026

19 people who take Enulose and Sinemet together, and have interactions are studied.

What are the common drug interactions of Enulose and Sinemet, by gender? *:

female:

Thyroid disorder (thyroid diseases)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Vomiting
Insomnia (sleeplessness)
Blood pressure orthostatic
Headache (pain in head)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Back pain

male:

Blood pressure increased
Chest pressure sensation (feeling of pressure on chest)
Anaemia (lack of blood)
Blood glucose increased
Body temperature decreased
Dizziness
Drug ineffective
Eye discharge
Foreign body trauma (injury by foreign particle)
Headache (pain in head)

What are the common drug interactions of Enulose and Sinemet, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Ataxia (loss of full control of bodily movements)
Back pain
Candidiasis (candidiasis or thrush is a fungal infection)
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
Colitis (inflammation of colon)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Contusion (a type of hematoma of tissue in which capillaries)

50-59:

Blood pressure orthostatic
Insomnia (sleeplessness)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Dysarthria (speech disorder)
Dysgraphia (impaired ability to learn to write)
Faecal incontinence (a lack of control over passing stool)
Gait disturbance
Headache (pain in head)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Anaemia (lack of blood)

60+:

Balance disorder
Blood pressure increased
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Suffocation feeling
Urinary tract infection
Visual impairment
Abasia (inability to walk)
Blood glucose increased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Orthostatic Hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up): 3 people, 15.79%
Dyskinesia (abnormality or impairment of voluntary movement): 2 people, 10.53%
Hypotension (abnormally low blood pressure): 2 people, 10.53%
Pain: 1 person, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.26%
Cough: 1 person, 5.26%
Dyspnea (difficult or laboured breathing): 1 person, 5.26%
Gastritis (inflammation of stomach): 1 person, 5.26%
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 1 person, 5.26%
Irritable Bowel Syndrome: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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