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Enzalutamide and Flutamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enzalutamide (enzalutamide) and Flutamide (flutamide). Common drug interactions include malaise among males.

The phase IV clinical study analyzes what interactions people have when they take Enzalutamide and Flutamide. It is created by eHealthMe based on reports of 100 people who take the same drugs from the FDA, and is updated regularly.

What is Enzalutamide?

Enzalutamide has active ingredients of enzalutamide. eHealthMe is studying from 14,018 Enzalutamide users. Check the latest studies of Enzalutamide.

What is Flutamide?

Flutamide has active ingredients of flutamide. eHealthMe is studying from 1,754 Flutamide users. Check the latest studies of Flutamide.

On Jul, 07, 2026

100 people who take Enzalutamide and Flutamide together, and have interactions are studied.

Enzalutamide and Flutamide drug interactions.

What are the common drug interactions of Enzalutamide and Flutamide, by gender? *:

female:

n/a

male:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Fatigue (feeling of tiredness)
  3. Prostate cancer
  4. Decreased appetite
  5. Loss of consciousness
  6. Urinary retention (the inability to completely or partially empty the bladder)
  7. Anaemia (lack of blood)
  8. Urinary tract infection
  9. Malignant neoplasm progression (cancer tumour came back)
  10. Weight decreased

What are the common drug interactions of Enzalutamide and Flutamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Nasopharyngitis (inflammation of the nasopharynx)
  3. Loss of consciousness
  4. Decreased appetite
  5. Prostate cancer
  6. Abdominal discomfort
  7. Malignant neoplasm progression (cancer tumour came back)
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Weight decreased
  10. Fall

What are the existing conditions these people have? *

  1. Prostate Cancer: 43 people, 43.00%
  2. Metastases To Bone (cancer spreads to bone): 18 people, 18.00%
  3. High Blood Pressure: 16 people, 16.00%
  4. Constipation: 13 people, 13.00%
  5. Urination - Painful: 9 people, 9.00%
  6. Prostate Cancer Metastatic: 8 people, 8.00%
  7. Insomnia (sleeplessness): 8 people, 8.00%
  8. Seasonal Allergy (allergic condition due to certain season): 7 people, 7.00%
  9. Spinal Stenosis (narrowing of spinal column): 6 people, 6.00%
  10. Dyslipidaemia (abnormal amount of lipids): 6 people, 6.00%

* Approximation only. Some reports may have incomplete information.

Do you take Enzalutamide and Flutamide?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Enzalutamide and Flutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enzalutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flutamide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enzalutamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flutamide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on enzalutamide and flutamide (the active ingredients of Enzalutamide and Flutamide, respectively), and Enzalutamide and Flutamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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