Epclusa and Nystatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epclusa (sofosbuvir; velpatasvir) and Nystatin (nystatin). Common drug interactions include headache among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Epclusa and Nystatin. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Epclusa?

Epclusa has active ingredients of sofosbuvir; velpatasvir. eHealthMe is studying from 12,120 Epclusa users. Check the latest studies of Epclusa.

What is Nystatin?

Nystatin has active ingredients of nystatin. It is often used in thrush. eHealthMe is studying from 33,567 Nystatin users. Check the latest studies of Nystatin.

On Jul, 31, 2026

33 people who take Epclusa and Nystatin together, and have interactions are studied.

What are the common drug interactions of Epclusa and Nystatin, by gender? *:

female:

Headache (pain in head)
Back pain
Drug ineffective
Fatigue (feeling of tiredness)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Oropharyngeal pain
Transplant rejection (a transplant material is not worked)
Abdominal hernia
Abdominal pain
Anastomotic ulcer

male:

Drug ineffective
Hepatitis c rna positive
Bile duct stenosis (abnormal narrowing of the common bile duct)
Bile output increased
Blood bilirubin increased
Bone density decreased
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Complications of transplanted lung
Death
Drug level below therapeutic

What are the common drug interactions of Epclusa and Nystatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bile duct stenosis (abnormal narrowing of the common bile duct)
Bile output increased
Bipolar disorder (mood disorder)
Blood bilirubin increased
Hepatitis c
Psychotic disorder
Transaminases increased

40-49:

Cellulitis (infection under the skin)
Fungal skin infection
Skin fissures (a crack in the skin)

50-59:

Drug ineffective
Hepatitis c rna positive
Hepatocellular carcinoma (liver cancer)
Liver transplant
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Bone density decreased
Drug resistance (reduction in effectiveness of a drug)
Emotional distress
Fracture

60+:

Drug ineffective
Hepatitis c
Insomnia (sleeplessness)
Mixed hepatocellular cholangiocarcinoma (a rare form of primary liver cancer)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Death
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Hepatitis C: 20 people, 60.61%

* Approximation only. Some reports may have incomplete information.

Do you take Epclusa and Nystatin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously