Epinephrine and Actemra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epinephrine (epinephrine) and Actemra (tocilizumab). Common drug interactions include urticaria among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Epinephrine and Actemra. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Epinephrine?

Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.

What is Actemra?

Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 102,759 Actemra users. Check the latest studies of Actemra.

On Jul, 31, 2026

69 people who take Epinephrine and Actemra together, and have interactions are studied.

Epinephrine and Actemra drug interactions.

What are the common drug interactions of Epinephrine and Actemra, by gender? *:

female:

Urticaria (rash of round, red welts on the skin that itch intensely)
Urinary tract infection
Blood pressure increased
Contusion (a type of hematoma of tissue in which capillaries)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Dizziness
Head injury
Impaired gastric emptying
Infusion site swelling
Skin discolouration (change of skin colour)

male:

Hypotension (abnormally low blood pressure)
Fatigue (feeling of tiredness)
Skin lesion
Skin mass
Somnolence (a state of near-sleep, a strong desire for sleep)
Testicular swelling (swelling of testes)
Upper limb fracture
Urinary hesitation (difficulty in beginning the flow of urine)
Abdominal infection
Chills (felling of cold)

What are the common drug interactions of Epinephrine and Actemra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Pneumonia

30-39:

Chills (felling of cold)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Disease progression
Oxygen saturation decreased
Pyrexia (fever)

40-49:

Abdominal infection
Acute respiratory failure
Cardiac arrest
Death
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Feeling hot
Flushing (the warm, red condition of human skin)
Heart rate increased
Hypotension (abnormally low blood pressure)

50-59:

Headache (pain in head)
Muscle tightness
Nausea (feeling of having an urge to vomit)
Palpitations (feelings or sensations that your heart is pounding or racing)
Skin infection
Rash
Anaemia (lack of blood)
Blood pressure increased
Breath sounds
Chest discomfort

60+:

Muscular weakness (muscle weakness)
Diarrhoea
Fall
Nausea (feeling of having an urge to vomit)
Abdominal pain upper
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Asthenia (weakness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 20 people, 28.99%
Immunodeficiency: 7 people, 10.14%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 7.25%
Primary Immunodeficiency Syndrome: 5 people, 7.25%
Pemphigoid (tense blisters on the skin): 4 people, 5.80%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 5.80%
Iridocyclitis (inflammation of the iris and ciliary body of the eye): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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