Epinephrine and Pramine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Epinephrine (epinephrine) and Pramine (imipramine hydrochloride). Common drug interactions include headache among females and infusion related reaction among males.
The phase IV clinical study analyzes what interactions people have when they take Epinephrine and Pramine. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Epinephrine?
Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.
What is Pramine?
Pramine has active ingredients of imipramine hydrochloride. eHealthMe is studying from 7,460 Pramine users. Check the latest studies of Pramine.
17 people who take Epinephrine and Pramine together, and have interactions are studied.

What are the common drug interactions of Epinephrine and Pramine, by gender? *:
female:
- Headache (pain in head)
- Sinusitis (inflammation of sinus)
- Nausea (feeling of having an urge to vomit)
- Fatigue (feeling of tiredness)
- Influenza
- Infusion related reaction
- Rectal prolapse (falling of rectum from normal place)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Upper respiratory tract infection
- Arthropathy
male:
- Infusion related reaction
- Headache (pain in head)
- Secretion discharge
- Sinusitis (inflammation of sinus)
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bowel movement irregularity
- Chest discomfort
- Migraine (headache)
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
What are the common drug interactions of Epinephrine and Pramine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Influenza
- Pyrexia (fever)
30-39:
n/a
40-49:
n/a
50-59:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Influenza
- Infusion related reaction
- Nausea (feeling of having an urge to vomit)
- Rectal prolapse (falling of rectum from normal place)
- Sinusitis (inflammation of sinus)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Upper respiratory tract infection
- Dyspnoea (difficult or laboured respiration)
60+:
- Headache (pain in head)
- Infusion related reaction
- Seasonal allergy (allergic condition due to certain season)
- Secretion discharge
- Arthralgia (joint pain)
- Asthenia (weakness)
- Bowel movement irregularity
- Chest discomfort
- Migraine (headache)
- Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 4 people, 23.53%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 23.53%
- Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 17.65%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 5.88%
- Reduction Of Increased Intracranial Pressure (reducing intracranial pressure): 1 person, 5.88%
- Performance Fear: 1 person, 5.88%
- Meningitis Neonatal (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges in neonate): 1 person, 5.88%
- Hydrocephalus (water on the brain): 1 person, 5.88%
- Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 1 person, 5.88%
- Cardiogenic Shock (inadequate circulation of blood): 1 person, 5.88%
* Approximation only. Some reports may have incomplete information.
Do you take Epinephrine and Pramine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Epinephrine (21,290 reports)
- Pramine (7,460 reports)
Browse all drug interactions of Epinephrine and Pramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Epinephrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pramine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epinephrine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pramine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on epinephrine and imipramine hydrochloride (the active ingredients of Epinephrine and Pramine, respectively), and Epinephrine and Pramine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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