Epipen and Arnuity ellipta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epipen (epinephrine) and Arnuity ellipta (fluticasone furoate). Common drug interactions include arthralgia among females and back disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Epipen and Arnuity ellipta. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

What is Arnuity ellipta?

Arnuity ellipta has active ingredients of fluticasone furoate. eHealthMe is studying from 3,482 Arnuity ellipta users. Check the latest studies of Arnuity ellipta.



On Jul, 06, 2026

49 people who take Epipen and Arnuity ellipta together, and have interactions are studied.

Epipen and Arnuity ellipta drug interactions.

What are the common drug interactions of Epipen and Arnuity Ellipta, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Bile duct cancer
  3. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  4. Dizziness
  5. Drug hypersensitivity
  6. Gastric cancer (stomach cancer)
  7. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Hepatic mass
  10. Sinusitis (inflammation of sinus)

male:

  1. Back disorder
  2. Cardiac disorder
  3. Infusion site scar
  4. Pain
  5. Gait disturbance
  6. Mobility decreased (ability to move is reduced)
  7. Spinal cord injury
  8. Muscle spasms (muscle contraction)
  9. Seasonal allergy (allergic condition due to certain season)
  10. Spinal cord injury lumbar (spinal cord injury at lumbar vertebrae region)

What are the common drug interactions of Epipen and Arnuity Ellipta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Injection site reaction

20-29:

n/a

30-39:

n/a

40-49:

  1. Back pain
  2. Dizziness
  3. Dyspnoea (difficult or laboured respiration)
  4. Loss of consciousness
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

  1. Bradycardia (abnormally slow heart action)
  2. Gait disturbance
  3. Intraneural cyst
  4. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Panic attack
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  8. Bone pain
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Immunodeficiency

60+:

  1. Heart rate increased
  2. Influenza like illness
  3. Viral infection
  4. Wound
  5. Gout (uric acid crystals building up in the body)
  6. Intervertebral disc disorder (spinal disc disorder)
  7. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  8. Blood pressure inadequately controlled
  9. Dehydration (dryness resulting from the removal of water)
  10. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 11 people, 22.45%
  2. Primary Immunodeficiency Syndrome: 9 people, 18.37%
  3. Asthma: 8 people, 16.33%
  4. Combined Immunodeficiency: 5 people, 10.20%
  5. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 8.16%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 8.16%
  7. Affective Disorder (mental disorder): 4 people, 8.16%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 8.16%
  9. Dizziness: 4 people, 8.16%
  10. Dry Mouth: 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Epipen and Arnuity ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epipen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arnuity ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epipen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arnuity ellipta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on epinephrine and fluticasone furoate (the active ingredients of Epipen and Arnuity ellipta, respectively), and Epipen and Arnuity ellipta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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