Epipen and Vicoprofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epipen (epinephrine) and Vicoprofen (hydrocodone bitartrate; ibuprofen). Common drug interactions include pneumonia among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Epipen and Vicoprofen. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Epipen?

Epipen has active ingredients of epinephrine. It is often used in anaphylaxis. eHealthMe is studying from 23,760 Epipen users. Check the latest studies of Epipen.

What is Vicoprofen?

Vicoprofen has active ingredients of hydrocodone bitartrate; ibuprofen. It is often used in pain. eHealthMe is studying from 1,842 Vicoprofen users. Check the latest studies of Vicoprofen.

On Jul, 10, 2026

22 people who take Epipen and Vicoprofen together, and have interactions are studied.

Epipen and Vicoprofen drug interactions.

What are the common drug interactions of Epipen and Vicoprofen, by gender? *:

female:

Pneumonia
Red blood cell count decreased
Restless legs syndrome (a powerful urge to move your legs)
Spinal fusion surgery
Tremor (trembling or shaking movements in one or more parts of your body)
Upper respiratory tract infection
Vulvovaginal dryness
Weight decreased
Dizziness
Drug ineffective

male:

Asthenia (weakness)
Arrhythmia (irregular heartbeat)
Hypoaesthesia (reduced sense of touch or sensation)
Joint swelling
Malaise (a feeling of general discomfort or uneasiness)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Oral candidiasis (fungal infection of mouth)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

What are the common drug interactions of Epipen and Vicoprofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Aphonia (inability to produce voice)
Candidiasis (candidiasis or thrush is a fungal infection)
Dizziness
Drug ineffective
Headache (pain in head)
Hunger
Insomnia (sleeplessness)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Tonsillar disorder (disease of tonsil)

40-49:

Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Gait disturbance
Pain in extremity
Peripheral swelling
Pneumonia

50-59:

Vomiting
Blood lactic acid increased
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Haematocrit
Haematocrit decreased
Haemoglobin decreased
Lymphocyte count decreased
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Red blood cell count decreased

60+:

n/a

What are the existing conditions these people have? *

High Blood Pressure: 6 people, 27.27%
Asthma: 5 people, 22.73%
High Blood Cholesterol: 5 people, 22.73%
Stress And Anxiety: 4 people, 18.18%
Cardiac Disorder: 4 people, 18.18%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 18.18%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 18.18%
Thyroid Diseases: 4 people, 18.18%
Mania (a state of abnormally elevated or irritable mood): 4 people, 18.18%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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