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Epivir and Avapro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Epivir (lamivudine) and Avapro (irbesartan). Common drug interactions include abdominal distension among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Epivir and Avapro. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Epivir?

Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.

What is Avapro?

Avapro has active ingredients of irbesartan. It is often used in high blood pressure. eHealthMe is studying from 19,840 Avapro users. Check the latest studies of Avapro.

On Jul, 10, 2026

12 people who take Epivir and Avapro together, and have interactions are studied.

Epivir and Avapro drug interactions.

What are the common drug interactions of Epivir and Avapro, by gender? *:

female:

  1. Abdominal distension
  2. Dyspepsia (indigestion)
  3. Fat disorder (inability to produce fat utilize enzyme)
  4. Flatulence (flatus expelled through the anus)
  5. Blood aldosterone decreased
  6. Cough
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Hypercholesterolaemia (high levels of cholesterol in the blood)
  10. Hyperkalaemia (damage to or disease of the kidney)

male:

  1. Chronic kidney disease
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Depression
  4. Disturbance in attention
  5. Emotional disorder
  6. Fear of disease
  7. Gout (uric acid crystals building up in the body)
  8. Immune system disorder
  9. Insomnia (sleeplessness)
  10. Mobility decreased (ability to move is reduced)

What are the common drug interactions of Epivir and Avapro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  3. Nephrogenic anaemia (anaemia due to kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Renal injury (kidney injury)
  6. Renal tubular necrosis (death of kidney tubules)
  7. Weight decreased

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Chronic kidney disease
  4. Emotional distress
  5. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  6. Pain
  7. Renal failure (kidney dysfunction)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Asthenia (weakness)
  4. Chronic kidney disease
  5. Depressed mood
  6. Depression
  7. Disturbance in attention
  8. Emotional disorder
  9. Emotional distress
  10. Fear of disease

60+:

  1. Chronic kidney disease
  2. Abdominal distension
  3. Proteinuria (presence of protein in the urine)
  4. Hyperlipidaemia (presence of excess lipids in the blood)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Anxiety
  7. Dyspepsia (indigestion)
  8. Emotional distress
  9. Fat disorder (inability to produce fat utilize enzyme)
  10. Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

  1. Hiv Infection: 6 people, 50.00%
  2. Pain: 3 people, 25.00%
  3. High Blood Cholesterol: 3 people, 25.00%
  4. Diarrhea: 3 people, 25.00%
  5. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 16.67%
  6. Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 2 people, 16.67%
  7. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 16.67%
  8. Headache (pain in head): 2 people, 16.67%
  9. Haemolytic Anaemia (anaemia due to haemolysis): 2 people, 16.67%
  10. Erection Problems: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Epivir and Avapro?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Epivir and Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Epivir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Avapro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epivir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Avapro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lamivudine and irbesartan (the active ingredients of Epivir and Avapro, respectively), and Epivir and Avapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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