Epivir and Pregabalin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Epivir (lamivudine) and Pregabalin (pregabalin). Common drug interactions include anhedonia among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Epivir and Pregabalin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Epivir?
Epivir has active ingredients of lamivudine. It is often used in hiv infection. eHealthMe is studying from 16,870 Epivir users. Check the latest studies of Epivir.
What is Pregabalin?
Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.
19 people who take Epivir and Pregabalin together, and have interactions are studied.

What are the common drug interactions of Epivir and Pregabalin, by gender? *:
female:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Decreased activity
- Emotional distress
- Fatigue (feeling of tiredness)
- Glomerulonephritis (a group of conditions that affect parts of the kidneys called glomeruli)
- Impaired work ability
- Mobility decreased (ability to move is reduced)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Mobility decreased (ability to move is reduced)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Osteoporosis (bones weak and more likely to break)
- Spinal compression fracture (fracture due to spinal compression on bone)
- Bone pain
- Dysuria (painful or difficult urination)
- General physical health deterioration (weak health status)
- Impaired work ability
What are the common drug interactions of Epivir and Pregabalin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Chronic kidney disease
- Emotional distress
- Impaired work ability
- Mobility decreased (ability to move is reduced)
- Renal impairment (severely reduced kidney function)
- Bone density decreased
- Decreased activity
- Fatigue (feeling of tiredness)
50-59:
- Emotional distress
- Nocturia (the need to get up in the night to urinate)
- Renal impairment (severely reduced kidney function)
- Chronic kidney disease
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
60+:
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Bone density decreased
- Bone pain
- Emotional distress
- Gait disturbance
What are the existing conditions these people have? *
- Hiv Infection: 16 people, 84.21%
- Isosporiasis (intestinal disease caused by the parasite isospora belli): 3 people, 15.79%
- Cough: 3 people, 15.79%
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 15.79%
- Hepatitis B: 3 people, 15.79%
- Toxoplasmosis (a parasitic disease caused by the protozoan toxoplasma gondii): 3 people, 15.79%
- Respiratory Tract Congestion (blockage on respiratory system): 3 people, 15.79%
- Iron Deficiency: 2 people, 10.53%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 10.53%
- Glomerulonephritis Membranous (nephritis with inflammation of the capillary loops in the renal glomeruli): 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Epivir and Pregabalin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Epivir (16,870 reports)
- Pregabalin (74,069 reports)
Browse all drug interactions of Epivir and Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Epivir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epivir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pregabalin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on lamivudine and pregabalin (the active ingredients of Epivir and Pregabalin, respectively), and Epivir and Pregabalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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