Eplerenone and Azithromycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eplerenone (eplerenone) and Azithromycin (azithromycin). Common drug interactions include asthma among females and asthma among males.

The phase IV clinical study analyzes what interactions people have when they take Eplerenone and Azithromycin. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

What is Azithromycin?

Azithromycin has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 40,716 Azithromycin users. Check the latest studies of Azithromycin.



On Jul, 16, 2026

41 people who take Eplerenone and Azithromycin together, and have interactions are studied.

Eplerenone and Azithromycin drug interactions.

What are the common drug interactions of Eplerenone and Azithromycin, by gender? *:

female:

  1. Asthma
  2. Cell death
  3. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  4. Cystitis (inflammation of the wall of the bladder)
  5. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  6. Influenza
  7. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  8. Upper respiratory tract infection
  9. Viral pharyngitis (inflammation of the throat or pharynx caused by viral infection)
  10. Abdominal pain

male:

  1. Asthma
  2. Cardiac disorder
  3. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  4. Fatigue (feeling of tiredness)
  5. Dizziness
  6. Immunosuppressant drug level increased
  7. Nausea (feeling of having an urge to vomit)
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Cough
  10. Depression

What are the common drug interactions of Eplerenone and Azithromycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal pain
  2. Dehydration (dryness resulting from the removal of water)
  3. Dizziness
  4. Drug hypersensitivity
  5. Nausea (feeling of having an urge to vomit)
  6. Pruritus (severe itching of the skin)
  7. Vomiting
  8. Asthma
  9. Cardiac arrest
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

  1. Asthma
  2. Dyspnoea (difficult or laboured respiration)
  3. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  4. Fatigue (feeling of tiredness)
  5. Cough
  6. Immunosuppressant drug level increased
  7. Ascites (accumulation of fluid in the abdominal cavity)
  8. Depression
  9. Dizziness
  10. Liver disorder (liver diseases)

What are the existing conditions these people have? *

  1. Asthma: 10 people, 24.39%
  2. Cardiac Failure: 5 people, 12.20%
  3. Respiratory Tract Infection: 3 people, 7.32%
  4. Oedema Peripheral (superficial swelling): 3 people, 7.32%
  5. Lipids Abnormal: 3 people, 7.32%
  6. Immunodeficiency Common Variable: 3 people, 7.32%
  7. Glomerulonephritis Membranoproliferative (a type of glomerulonephritis caused by deposits in the kidney glomerular mesangium and basement membrane (gbm) thickening): 3 people, 7.32%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 7.32%
  9. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

Do you take Eplerenone and Azithromycin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Eplerenone and Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eplerenone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Azithromycin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eplerenone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Azithromycin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on eplerenone and azithromycin (the active ingredients of Eplerenone and Azithromycin, respectively), and Eplerenone and Azithromycin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: