Eplerenone and Cosentyx drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eplerenone (eplerenone) and Cosentyx (secukinumab). Common drug interactions include ankylosing spondylitis among females and ankylosing spondylitis among males.

The phase IV clinical study analyzes what interactions people have when they take Eplerenone and Cosentyx. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Eplerenone?

Eplerenone has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 9,979 Eplerenone users. Check the latest studies of Eplerenone.

What is Cosentyx?

Cosentyx has active ingredients of secukinumab. It is often used in psoriatic arthritis. eHealthMe is studying from 187,247 Cosentyx users. Check the latest studies of Cosentyx.

On Aug, 02, 2026

34 people who take Eplerenone and Cosentyx together, and have interactions are studied.

Eplerenone and Cosentyx drug interactions.

What are the common drug interactions of Eplerenone and Cosentyx, by gender? *:

female:

Ankylosing spondylitis (type of arthritis affecting the spine)
Cardiac failure
Depressed mood
Lower respiratory tract infection
Oropharyngeal pain
Rhinalgia (pain in the nose)
Nasal discomfort
Abdominal pain
Bacterial infection
Diarrhoea

male:

Ankylosing spondylitis (type of arthritis affecting the spine)
Fatigue (feeling of tiredness)
Blood alkaline phosphatase increased
Blood triglycerides increased
Drug intolerance (drug sensitivity)
Dry mouth
Feeling cold
Nasopharyngitis (inflammation of the nasopharynx)
Nocturia (the need to get up in the night to urinate)
Pulmonary oedema (fluid accumulation in the lungs)

What are the common drug interactions of Eplerenone and Cosentyx, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Death

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Bacterial infection
Diarrhoea
Dizziness
Inflammatory bowel disease

60+:

Blood alkaline phosphatase increased
Blood triglycerides increased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Muscle spasms (muscle contraction)
Pain

What are the existing conditions these people have? *

Ankylosing Spondylitis (type of arthritis affecting the spine): 12 people, 35.29%
Psoriasis (immune-mediated disease that affects the skin): 8 people, 23.53%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 8.82%
Pain: 3 people, 8.82%
Laxative Supportive Care: 3 people, 8.82%
Gout (uric acid crystals building up in the body): 3 people, 8.82%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 3 people, 8.82%
Cardiac Failure Chronic: 3 people, 8.82%
Cardiac Disorder: 3 people, 8.82%
Bronchial Disorder: 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

Do you take Eplerenone and Cosentyx?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously