Ergocalciferol and Epidiolex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ergocalciferol (ergocalciferol) and Epidiolex (cannabidiol). Common drug interactions include pneumatosis among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Ergocalciferol and Epidiolex. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Ergocalciferol?

Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.

What is Epidiolex?

Epidiolex has active ingredients of cannabidiol. eHealthMe is studying from 18,763 Epidiolex users. Check the latest studies of Epidiolex.



On Jul, 15, 2026

30 people who take Ergocalciferol and Epidiolex together, and have interactions are studied.

Ergocalciferol and Epidiolex drug interactions.

What are the common drug interactions of Ergocalciferol and Epidiolex, by gender? *:

female:

  1. Pneumatosis (air or gas in an abnormal location in the body)
  2. Hospitalisation
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

male:

  1. Acute respiratory failure
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Death
  4. Cardiac arrest
  5. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  6. Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
  7. Hypotension (abnormally low blood pressure)
  8. Lactic acidosis (low ph in body tissues)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Pulse absent

What are the common drug interactions of Ergocalciferol and Epidiolex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Acute respiratory failure
  2. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  3. Pyrexia (fever)
  4. Respiratory tract infection
  5. Biliary tract disorder
  6. Gastritis (inflammation of stomach)
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Respiration (transport of oxygen from the outside air to the cells within tissues)
  9. Urinary tract infection
  10. Viral infection

10-19:

  1. Pneumatosis (air or gas in an abnormal location in the body)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

20-29:

  1. Spinal fracture (fracture in one of vertebrae)
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  3. Diarrhoea
  4. Insomnia (sleeplessness)
  5. Rash
  6. Seasonal allergy (allergic condition due to certain season)

30-39:

  1. Diarrhoea
  2. Optic neuropathy (optic nerve damage)
  3. Seasonal allergy (allergic condition due to certain season)
  4. Spinal fracture (fracture in one of vertebrae)
  5. Visual field defect

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 13 people, 43.33%
  2. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 26.67%
  3. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 7 people, 23.33%
  4. Seizure Cluster (small group of seizure): 3 people, 10.00%
  5. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 10.00%
  6. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 10.00%
  7. Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 2 people, 6.67%
  8. Pain: 2 people, 6.67%
  9. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 6.67%
  10. Idiopathic Generalised Epilepsy (epileptic disorders that are believed to have a strong underlying genetic basis): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ergocalciferol and Epidiolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ergocalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Epidiolex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ergocalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Epidiolex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ergocalciferol and cannabidiol (the active ingredients of Ergocalciferol and Epidiolex, respectively), and Ergocalciferol and Epidiolex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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