Erythromycin and Ketek drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Erythromycin (erythromycin) and Ketek (telithromycin). Common drug interactions include splenomegaly among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Erythromycin and Ketek. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Erythromycin?

Erythromycin has active ingredients of erythromycin. It is often used in acne. eHealthMe is studying from 12,563 Erythromycin users. Check the latest studies of Erythromycin.

What is Ketek?

Ketek has active ingredients of telithromycin. eHealthMe is studying from 4,631 Ketek users. Check the latest studies of Ketek.

On Jul, 28, 2026

40 people who take Erythromycin and Ketek together, and have interactions are studied.

Erythromycin and Ketek drug interactions.

What are the common drug interactions of Erythromycin and Ketek, by gender? *:

female:

Splenomegaly (enlargement of spleen)
Erosive oesophagitis (acid reflux disease can cause tissue damage in the oesophagus over time)
Faeces pale
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Weight decreased
Bone disorder
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Portal hypertension (increase in the blood pressure within a system of veins called the portal venous system)
Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
Hepatic failure (liver failure)

male:

Asthenia (weakness)
Hepatomegaly (abnormal enlargement of the liver)
Ascites (accumulation of fluid in the abdominal cavity)
Back pain
Constipation
Cough
Fatigue (feeling of tiredness)
Hepatic enzyme increased
Hepatitis (inflammation of the liver)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

What are the common drug interactions of Erythromycin and Ketek, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Alanine aminotransferase increased
Anaemia (lack of blood)
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood bilirubin increased
Blood lactate dehydrogenase increased
Change of bowel habit
Chills (felling of cold)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

30-39:

Asthenia (weakness)
Hepatomegaly (abnormal enlargement of the liver)
Ammonia increased
Confusional state
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Weight increased
Abdominal discomfort
Abdominal distension
Abdominal pain
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)

40-49:

Chronic kidney disease

50-59:

Dehydration (dryness resulting from the removal of water)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Pain in extremity
Pleurisy (inflammation of the pleurae, which causes pain when breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Rheumatoid factor increased
Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)

60+:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Escherichia infection (bacterial infection by escherichia coli)
Eye irritation
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)
Iritis (painful inflammation of the iris of the eye)
Malaise (a feeling of general discomfort or uneasiness)

What are the existing conditions these people have? *

Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 16 people, 40.00%
Pneumonia: 5 people, 12.50%
High Blood Pressure: 5 people, 12.50%
Sinusitis (inflammation of sinus): 4 people, 10.00%
Glossitis (infection of tongue with soreness): 4 people, 10.00%
Bronchitis Chronic (inflammation of the mucous membrane in the bronchial tubes- chronic): 4 people, 10.00%
Asthma: 4 people, 10.00%
Infection: 3 people, 7.50%
Cough: 3 people, 7.50%
Type 2 Diabetes: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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