Esbriet and Ranolazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Esbriet (pirfenidone) and Ranolazine (ranolazine). Common drug interactions include chronic obstructive pulmonary disease among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Esbriet and Ranolazine. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Esbriet?

Esbriet has active ingredients of pirfenidone. eHealthMe is studying from 39,858 Esbriet users. Check the latest studies of Esbriet.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

On Jul, 19, 2026

26 people who take Esbriet and Ranolazine together, and have interactions are studied.

Esbriet and Ranolazine drug interactions.

What are the common drug interactions of Esbriet and Ranolazine, by gender? *:

female:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Idiopathic pulmonary fibrosis (chronic lung disease)
Respiratory failure (inadequate gas exchange by the respiratory system)
Cardiac disorder
Lung disorder (lung disease)
Respiratory disorder (respiratory disease)
Cardiomyopathy (weakening of the heart muscle)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Acute respiratory failure
Cataract (clouding of the lens inside the eye)

male:

Decreased appetite
Death
Dizziness
Fatigue (feeling of tiredness)
Lethargy (tiredness)
Blood sodium decreased
Pain
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest

What are the common drug interactions of Esbriet and Ranolazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Blood sodium decreased
Decreased appetite
Pain
Acute respiratory failure
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac arrest
Cardiac disorder

What are the existing conditions these people have? *

Idiopathic Pulmonary Fibrosis (chronic lung disease): 18 people, 69.23%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 6 people, 23.08%
Nausea (feeling of having an urge to vomit): 5 people, 19.23%
Dyspnea (difficult or laboured breathing): 5 people, 19.23%
Cough: 5 people, 19.23%
Chest Pain: 5 people, 19.23%
Wheezing (a high-pitched whistling sound made while you breath): 4 people, 15.38%
Hypersensitivity: 4 people, 15.38%
Interstitial Lung Disease: 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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