Esidrix and Metoclopramide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Esidrix (hydrochlorothiazide) and Metoclopramide (metoclopramide hydrochloride). Common drug interactions include hypokalaemia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Esidrix and Metoclopramide. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Esidrix?

Esidrix has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 1,846 Esidrix users. Check the latest studies of Esidrix.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

On Jul, 12, 2026

16 people who take Esidrix and Metoclopramide together, and have interactions are studied.

Esidrix and Metoclopramide drug interactions.

What are the common drug interactions of Esidrix and Metoclopramide, by gender? *:

female:

Hypokalaemia (low potassium)
Abdominal pain upper
Blood creatinine increased
Blood uric acid increased
Chest discomfort
Gastrointestinal inflammation (inflammation of stomach and intestine)
Herpes zoster
Leukocytosis (increased white blood cells)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

male:

Arthralgia (joint pain)
Circulatory collapse
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysphagia (a condition in which swallowing is difficult or painful)
Haematocrit decreased
Haemoglobin decreased
Hemiplegia (paralysis of one side of the body)
Infarction (obstruction of the blood supply to an organ or region of tissue)
Micturition urgency (urgency to pass the urine)

What are the common drug interactions of Esidrix and Metoclopramide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain upper
Blood creatinine increased
Blood uric acid increased
Chest discomfort
Gastrointestinal inflammation (inflammation of stomach and intestine)
Herpes zoster
Hypokalaemia (low potassium)
Leukocytosis (increased white blood cells)
Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

60+:

Dehydration (dryness resulting from the removal of water)
Renal impairment (severely reduced kidney function)
Nephropathy (damage to or disease of a kidney)
Pain in extremity
Antidepressant drug level above therapeutic
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Back pain

What are the existing conditions these people have? *

Pain: 4 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 18.75%
Cardiac Failure: 3 people, 18.75%
Depression: 3 people, 18.75%
Dyspnea (difficult or laboured breathing): 3 people, 18.75%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 3 people, 18.75%
Agitation (state of anxiety or nervous excitement): 3 people, 18.75%
Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 2 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 2 people, 12.50%
Arrhythmias (irregular heartbeat): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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