Eskalith and Protonix drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Eskalith (lithium carbonate) and Protonix (pantoprazole sodium). Common drug interactions include hyperglycaemia among females and diabetes mellitus among males.
The phase IV clinical study analyzes what interactions people have when they take Eskalith and Protonix. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Eskalith?
Eskalith has active ingredients of lithium carbonate. eHealthMe is studying from 1,448 Eskalith users. Check the latest studies of Eskalith.
What is Protonix?
Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.
19 people who take Eskalith and Protonix together, and have interactions are studied.

What are the common drug interactions of Eskalith and Protonix, by gender? *:
female:
- Hyperglycaemia (high blood sugar)
- Hypertension (high blood pressure)
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypoaesthesia facial (reduced sense of touch or sensation on face)
- Infusion site haemorrhage (bleeding from infusion site)
- Infusion site swelling
- Loss of consciousness
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
- Malaise (a feeling of general discomfort or uneasiness)
- Mania (a state of abnormally elevated or irritable mood)
male:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Acute respiratory distress syndrome
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Asthenia (weakness)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Joint swelling
- Laryngeal pain
- Limb injury
- Obesity (having too much body fat)
What are the common drug interactions of Eskalith and Protonix, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Back pain
- Bipolar disorder (mood disorder)
- Borderline personality disorder
- Chest pain
- Dental caries
- Depression
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug dependence
- Dyspnoea (difficult or laboured respiration)
- Headache (pain in head)
30-39:
- Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diabetes mellitus inadequate control
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Joint swelling
- Laryngeal pain
- Limb injury
- Oedema peripheral (superficial swelling)
- Sinusitis (inflammation of sinus)
40-49:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Abdominal pain upper
- Acute respiratory distress syndrome
- Adverse drug reaction
- Ankle fracture
- Cerebral haemorrhage (bleeding within the brain)
- Chills (felling of cold)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Cough
- Decreased appetite
50-59:
- Depression
- Device related infection
- Diabetic coma
- Dizziness
- Dyskinesia (abnormality or impairment of voluntary movement)
- Emotional disorder
- Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
- Eye pain
- Eyelid ptosis (falling of the upper or lower eyelid)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
60+:
- Drug ineffective
- Mania (a state of abnormally elevated or irritable mood)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
What are the existing conditions these people have? *
- Bipolar Disorder (mood disorder): 4 people, 21.05%
- Depression: 4 people, 21.05%
- Stress And Anxiety: 4 people, 21.05%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
- Sleep Disorder: 2 people, 10.53%
- Wheezing (a high-pitched whistling sound made while you breath): 1 person, 5.26%
- Ill-Defined Disorder: 1 person, 5.26%
- Affective Disorder (mental disorder): 1 person, 5.26%
- Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.26%
- Constipation: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Eskalith and Protonix?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Eskalith and Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Eskalith:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Protonix:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Eskalith and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Protonix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lithium carbonate and pantoprazole sodium (the active ingredients of Eskalith and Protonix, respectively), and Eskalith and Protonix (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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