Esomeprazole sodium and Metolazone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Esomeprazole sodium (esomeprazole sodium) and Metolazone (metolazone). Common drug interactions include delirium among females and electrolyte imbalance among males.

The phase IV clinical study analyzes what interactions people have when they take Esomeprazole sodium and Metolazone. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Esomeprazole sodium?

Esomeprazole sodium has active ingredients of esomeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,583 Esomeprazole sodium users. Check the latest studies of Esomeprazole sodium.

What is Metolazone?

Metolazone has active ingredients of metolazone. It is often used in swelling. eHealthMe is studying from 13,411 Metolazone users. Check the latest studies of Metolazone.

On Jul, 16, 2026

19 people who take Esomeprazole sodium and Metolazone together, and have interactions are studied.

Esomeprazole sodium and Metolazone drug interactions.

What are the common drug interactions of Esomeprazole Sodium and Metolazone, by gender? *:

female:

Delirium (wild excitement)
Visual impairment
Fatigue (feeling of tiredness)
Agitation (state of anxiety or nervous excitement)
Confusional state
Decreased appetite
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination, visual (seeing things that aren't there)
Insomnia (sleeplessness)
Pseudodementia (severe form of depression that results from a progressive brain disorder in which cognitive changes mimic those of dementia)

male:

Electrolyte imbalance
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Myopathy (a muscular disease in which the muscle fibres do not function)
Cardiac failure
Heart rate irregular
Pulmonary hypertension (increase in blood pressure in the lung artery)

What are the common drug interactions of Esomeprazole Sodium and Metolazone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Neuropathy peripheral (surface nerve damage)

60+:

Electrolyte imbalance
Renal failure acute (rapid kidney dysfunction)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Psoriasis (immune-mediated disease that affects the skin)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal tubular necrosis (death of kidney tubules)
Respiratory failure (inadequate gas exchange by the respiratory system)
Vision blurred
Weight decreased
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)

What are the existing conditions these people have? *

Sleep Disorder: 10 people, 52.63%
Diarrhea: 9 people, 47.37%
Pain: 5 people, 26.32%
Fever: 4 people, 21.05%
Candida Osteomyelitis (infection of bone by candida): 3 people, 15.79%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.79%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 10.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 10.53%
Thyroid Diseases: 1 person, 5.26%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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