Estazolam and Lamotrigine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estazolam (estazolam) and Lamotrigine (lamotrigine). Common drug interactions include hypoaesthesia among females and toxic epidermal necrolysis among males.

The phase IV clinical study analyzes what interactions people have when they take Estazolam and Lamotrigine. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Estazolam?

Estazolam has active ingredients of estazolam. It is often used in insomnia. eHealthMe is studying from 2,758 Estazolam users. Check the latest studies of Estazolam.

What is Lamotrigine?

Lamotrigine has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 76,638 Lamotrigine users. Check the latest studies of Lamotrigine.

On Jul, 13, 2026

47 people who take Estazolam and Lamotrigine together, and have interactions are studied.

Estazolam and Lamotrigine drug interactions.

What are the common drug interactions of Estazolam and Lamotrigine, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Nerve compression
Neutropenia (an abnormally low number of neutrophils)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Thrombocytopenia (decrease of platelets in blood)
Ulcer
Pain
Confusional state

male:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Cardiogenic shock (inadequate circulation of blood)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Delirium (wild excitement)
Depressed mood
Drug ineffective
Epidermal necrosis (skin condition that is usually caused by a reaction to drugs)
Erythema (redness of the skin)

What are the common drug interactions of Estazolam and Lamotrigine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Affective disorder (mental disorder)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Depressed mood
Drug ineffective
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)
Sedation

30-39:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Acute generalised exanthematous pustulosis (acute febrile drug eruption)
Depression
Drug ineffective
Speech disorder
Apoptosis
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Epidermal necrosis (skin condition that is usually caused by a reaction to drugs)
Erythema (redness of the skin)

40-49:

Facial bones fracture (bone fracture of face)
Head injury
Loss of consciousness
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Agitation (state of anxiety or nervous excitement)
Antidepressant drug level increased
Confusional state
Dehydration (dryness resulting from the removal of water)
Poriomania (unconscious tendency to walk away from home)
Psychiatric symptom

50-59:

Thrombocytopenia (decrease of platelets in blood)
Aggression
Altered state of consciousness (altered state of mind)
Irritability
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Nausea (feeling of having an urge to vomit)
Catatonia (unresponsive to external stimuli)
Confusional state
Decreased appetite
Delirium (wild excitement)

60+:

Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Pain
Pain in extremity
Panic attack
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Cardiogenic shock (inadequate circulation of blood)
Delirium (wild excitement)

What are the existing conditions these people have? *

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 13 people, 27.66%
Stress And Anxiety: 10 people, 21.28%
Affective Disorder (mental disorder): 9 people, 19.15%
Constipation: 8 people, 17.02%
Panic Disorder: 7 people, 14.89%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 14.89%
Anaemia (lack of blood): 7 people, 14.89%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 7 people, 14.89%
Back Disorder: 7 people, 14.89%
Back Pain: 7 people, 14.89%

* Approximation only. Some reports may have incomplete information.

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