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Estrace and Multaq drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estrace (estradiol) and Multaq (dronedarone hydrochloride). Common drug interactions include blood urine present among females.

The phase IV clinical study analyzes what interactions people have when they take Estrace and Multaq. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

What is Multaq?

Multaq has active ingredients of dronedarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 11,053 Multaq users. Check the latest studies of Multaq.

On Aug, 04, 2026

18 people who take Estrace and Multaq together, and have interactions are studied.

Estrace and Multaq drug interactions.

What are the common drug interactions of Estrace and Multaq, by gender? *:

female:

  1. Blood urine present
  2. Cardiac disorder
  3. Dysuria (painful or difficult urination)
  4. Fibromyalgia (a long-term condition which causes pain all over the body)
  5. Fungal infection
  6. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  7. Heart rate decreased
  8. Hyperhidrosis (abnormally increased sweating)
  9. Infection
  10. Migraine (headache)

male:

n/a

What are the common drug interactions of Estrace and Multaq, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Blood urine present
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Fungal infection
  4. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  5. Heart rate decreased
  6. Hyperhidrosis (abnormally increased sweating)
  7. Infection
  8. Migraine (headache)
  9. Muscle spasms (muscle contraction)
  10. Oropharyngeal pain

What are the existing conditions these people have? *

  1. Back Pain: 9 people, 50.00%
  2. Thyroid Diseases: 7 people, 38.89%
  3. High Blood Cholesterol: 7 people, 38.89%
  4. Infection: 6 people, 33.33%
  5. Diabetes: 4 people, 22.22%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 16.67%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%
  8. Lung Neoplasm Malignant (cancer tumour of lung): 1 person, 5.56%
  9. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 1 person, 5.56%
  10. Dyspnea (difficult or laboured breathing): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Estrace and Multaq?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Estrace and Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estrace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Multaq:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estrace and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Multaq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on estradiol and dronedarone hydrochloride (the active ingredients of Estrace and Multaq, respectively), and Estrace and Multaq (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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