Estrace and Rocaltrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estrace (estradiol) and Rocaltrol (calcitriol). Common drug interactions include urinary tract infection among females.

The phase IV clinical study analyzes what interactions people have when they take Estrace and Rocaltrol. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Estrace?

Estrace has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 16,703 Estrace users. Check the latest studies of Estrace.

What is Rocaltrol?

Rocaltrol has active ingredients of calcitriol. It is often used in hypoparathyroidism. eHealthMe is studying from 7,562 Rocaltrol users. Check the latest studies of Rocaltrol.

On Jul, 28, 2026

23 people who take Estrace and Rocaltrol together, and have interactions are studied.

Estrace and Rocaltrol drug interactions.

What are the common drug interactions of Estrace and Rocaltrol, by gender? *:

female:

Urinary tract infection
Hypoaesthesia (reduced sense of touch or sensation)
Chills (felling of cold)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Decreased appetite
Encephalopathy (functioning of the brain is affected by some agent or condition)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Hydronephrosis (water inside the kidney)
Hypercholesterolaemia (high levels of cholesterol in the blood)
Hypertriglyceridaemia (excess of triglycerides in the blood)

male:

n/a

What are the common drug interactions of Estrace and Rocaltrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Dyspepsia (indigestion)
Hypersensitivity
Oedema (fluid collection in tissue)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

50-59:

Hypoaesthesia (reduced sense of touch or sensation)
Optic ischaemic neuropathy (optic nerve damage due to lack of blood supply)
Procedural pain
Tinnitus (a ringing in the ears)
Back pain
Bedridden
Chills (felling of cold)
Decreased appetite
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Gait disturbance

60+:

Abdominal pain
Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nephrogenic anaemia (anaemia due to kidney disease)
Pain
Pneumonia
Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)
Small intestinal obstruction (blockage in small intestine)
Cardiomyopathy (weakening of the heart muscle)
Chronic kidney disease

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 34.78%
Pain: 5 people, 21.74%
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly): 4 people, 17.39%
Back Pain: 4 people, 17.39%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 17.39%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 13.04%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 13.04%
Nausea (feeling of having an urge to vomit): 2 people, 8.70%
Irritable Bowel Syndrome: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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