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Estraderm and Stilnoct drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Estraderm (estradiol) and Stilnoct (zolpidem tartrate). Common drug interactions include balance disorder among females.

The phase IV clinical study analyzes what interactions people have when they take Estraderm and Stilnoct. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Estraderm?

Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.

What is Stilnoct?

Stilnoct has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 468 Stilnoct users. Check the latest studies of Stilnoct.

On Jul, 12, 2026

11 people who take Estraderm and Stilnoct together, and have interactions are studied.

Estraderm and Stilnoct drug interactions.

What are the common drug interactions of Estraderm and Stilnoct, by gender? *:

female:

  1. Balance disorder
  2. Deafness
  3. Fatigue (feeling of tiredness)
  4. Femur fracture
  5. Gait disturbance
  6. Hypoacusis (loss of hearing)
  7. Lower limb fracture
  8. Pain in extremity
  9. Swelling

male:

n/a

What are the common drug interactions of Estraderm and Stilnoct, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Balance disorder
  2. Deafness
  3. Fatigue (feeling of tiredness)
  4. Femur fracture
  5. Gait disturbance
  6. Hypoacusis (loss of hearing)
  7. Lower limb fracture
  8. Pain in extremity
  9. Swelling

60+:

n/a

What are the existing conditions these people have? *

  1. Type 1 Diabetes: 11 people, 100.00%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 100.00%
  3. Oestrogen Deficiency (lack of estrogens): 11 people, 100.00%
  4. Foot Fracture: 11 people, 100.00%
  5. Blood Testosterone Decreased: 11 people, 100.00%
  6. Dehydroepiandrosterone Decreased: 10 people, 90.91%
  7. Blood Pressure Abnormal: 5 people, 45.45%
  8. Sleep Disorder: 1 person, 9.09%
  9. High Blood Pressure: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Estraderm and Stilnoct?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Estraderm and Stilnoct:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Estraderm:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Stilnoct:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Estraderm and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Stilnoct and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on estradiol and zolpidem tartrate (the active ingredients of Estraderm and Stilnoct, respectively), and Estraderm and Stilnoct (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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