Estraderm and Zoledronic drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Estraderm (estradiol) and Zoledronic (zoledronic acid). Common drug interactions include balance disorder among females.
The phase IV clinical study analyzes what interactions people have when they take Estraderm and Zoledronic. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Estraderm?
Estraderm has active ingredients of estradiol. It is often used in hormone replacement therapy. eHealthMe is studying from 3,441 Estraderm users. Check the latest studies of Estraderm.
What is Zoledronic?
Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.
12 people who take Estraderm and Zoledronic together, and have interactions are studied.

What are the common drug interactions of Estraderm and Zoledronic, by gender? *:
female:
- Balance disorder
- Deafness
- Drug ineffective
- Renal cancer (cancer of kidney)
- Fatigue (feeling of tiredness)
- Femur fracture
- Gait disturbance
- Hypoacusis (loss of hearing)
- Lower limb fracture
- Pain in extremity
male:
n/a
What are the common drug interactions of Estraderm and Zoledronic, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Balance disorder
- Deafness
- Fatigue (feeling of tiredness)
- Femur fracture
- Gait disturbance
- Hypoacusis (loss of hearing)
- Lower limb fracture
- Pain in extremity
- Swelling
60+:
n/a
What are the existing conditions these people have? *
- Type 1 Diabetes: 11 people, 91.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 91.67%
- Oestrogen Deficiency (lack of estrogens): 11 people, 91.67%
- Insomnia (sleeplessness): 11 people, 91.67%
- Foot Fracture: 11 people, 91.67%
- Blood Testosterone Decreased: 11 people, 91.67%
- Dehydroepiandrosterone Decreased: 10 people, 83.33%
- Blood Pressure Abnormal: 5 people, 41.67%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 8.33%
- Sleep Disorder: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Estraderm and Zoledronic?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Estraderm (3,441 reports)
- Zoledronic (29,812 reports)
Browse all drug interactions of Estraderm and Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Estraderm:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zoledronic:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Estraderm and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoledronic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estradiol and zoledronic acid (the active ingredients of Estraderm and Zoledronic, respectively), and Estraderm and Zoledronic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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