1. Home
  2. Analysis
  3. Eszopiclone
  4. Vortioxetine

Eszopiclone and Vortioxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Eszopiclone (eszopiclone) and Vortioxetine (vortioxetine). Common drug interactions include postictal state among females and nasopharyngitis among males.

The phase IV clinical study analyzes what interactions people have when they take Eszopiclone and Vortioxetine. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Eszopiclone?

Eszopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 4,259 Eszopiclone users. Check the latest studies of Eszopiclone.

What is Vortioxetine?

Vortioxetine has active ingredients of vortioxetine. eHealthMe is studying from 2,440 Vortioxetine users. Check the latest studies of Vortioxetine.

On Aug, 09, 2026

13 people who take Eszopiclone and Vortioxetine together, and have interactions are studied.

Eszopiclone and Vortioxetine drug interactions.

What are the common drug interactions of Eszopiclone and Vortioxetine, by gender? *:

female:

  1. Postictal state
  2. Sedation
  3. Tongue biting
  4. Tongue haemorrhage (bleeding from tongue)
  5. Vomiting
  6. Completed suicide (act of taking one's own life)
  7. Suicidal behaviour
  8. Abdominal distension
  9. Blood pressure increased
  10. Exposure to toxic agent

male:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Nausea (feeling of having an urge to vomit)
  3. Type 2 diabetes mellitus

What are the common drug interactions of Eszopiclone and Vortioxetine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Suicidal behaviour
  3. Abdominal distension
  4. Nausea (feeling of having an urge to vomit)
  5. Type 2 diabetes mellitus

30-39:

n/a

40-49:

  1. Blood pressure increased
  2. Heart rate increased
  3. Muscle twitching
  4. Postictal state
  5. Sedation
  6. Tongue biting
  7. Tongue haemorrhage (bleeding from tongue)
  8. Vomiting

50-59:

n/a

60+:

  1. Completed suicide (act of taking one's own life)
  2. Exposure to toxic agent

What are the existing conditions these people have? *

  1. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 4 people, 30.77%
  2. Lipids Abnormal: 2 people, 15.38%
  3. Type 2 Diabetes: 1 person, 7.69%
  4. Suicide Attempt: 1 person, 7.69%
  5. Sleep Disorder: 1 person, 7.69%
  6. Panic Disorder: 1 person, 7.69%
  7. High Blood Pressure: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Eszopiclone and Vortioxetine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Eszopiclone and Vortioxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Eszopiclone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vortioxetine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Eszopiclone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vortioxetine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on eszopiclone and vortioxetine (the active ingredients of Eszopiclone and Vortioxetine, respectively), and Eszopiclone and Vortioxetine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.