Eszopiclone and Vyvanse drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Eszopiclone (eszopiclone) and Vyvanse (lisdexamfetamine dimesylate). Common drug interactions include respiratory tract infection among females and drug ineffective among males.
The phase IV clinical study analyzes what interactions people have when they take Eszopiclone and Vyvanse. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.
What is Eszopiclone?
Eszopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 4,258 Eszopiclone users. Check the latest studies of Eszopiclone.
What is Vyvanse?
Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 35,868 Vyvanse users. Check the latest studies of Vyvanse.
41 people who take Eszopiclone and Vyvanse together, and have interactions are studied.

What are the common drug interactions of Eszopiclone and Vyvanse, by gender? *:
female:
- Respiratory tract infection
- Sinusitis (inflammation of sinus)
- Productive cough
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Nasopharyngitis (inflammation of the nasopharynx)
- Weight increased
- Angioplasty
- Fatigue (feeling of tiredness)
- Suicidal ideation
male:
- Drug ineffective
- Anxiety
- Balance disorder
- Blood urine present
- Bone density decreased
- Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
- Dysstasia (difficulty in standing)
- Emotional distress
- Gait disturbance
- General physical health deterioration (weak health status)
What are the common drug interactions of Eszopiclone and Vyvanse, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Acute psychosis (period of mentally unstable behaviour)
- Anxiety
- Hypertension (high blood pressure)
- Nasopharyngitis (inflammation of the nasopharynx)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Somnambulism (sleep walking)
- Weight increased
30-39:
- Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
- Discomfort
- Pancreatitis relapsing
- Rash
- Antinuclear antibody positive
- Arthralgia (joint pain)
- Asthma
- Blepharospasm (any abnormal contraction or twitch of the eyelid)
- Blood pressure increased
- Chest pain
40-49:
- Peripheral swelling
- Abdominal pain
- Blood pressure increased
- Heart rate increased
- Hepatic failure (liver failure)
- Loss of consciousness
- Oral candidiasis (fungal infection of mouth)
- Pain
- Pyrexia (fever)
- Rash
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dry mouth
- Dysgeusia (disorder of the sense of taste)
- Oral mucosal blistering (mouth ulcer)
- Anaemia (lack of blood)
60+:
- Productive cough
- Respiratory tract infection
- Sinusitis (inflammation of sinus)
- Dyspnoea (difficult or laboured respiration)
- Pneumonia
- Anger
- Anxiety
- Nasopharyngitis (inflammation of the nasopharynx)
- Obstruction
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 46.34%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 34.15%
- Drowsiness: 6 people, 14.63%
- Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 7.32%
* Approximation only. Some reports may have incomplete information.
Do you take Eszopiclone and Vyvanse?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Eszopiclone (4,258 reports)
- Vyvanse (35,868 reports)
Browse all drug interactions of Eszopiclone and Vyvanse:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Eszopiclone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vyvanse:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Eszopiclone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vyvanse and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Najib J, Wimer D, Zeng J, Lam KW, Romanyak N, Paige Morgan E, Thadavila A, "Review of Lisdexamfetamine Dimesylate in Adults With Attention-Deficit/Hyperactivity Disorder", Journal of central nervous system disease, 2017 Aug .
- Maneeton N, Maneeton B, Suttajit S, Reungyos J, Srisurapanont M, Martin SD, "Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD", Drug design, development and therapy, 2017 Jan .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Maneeton B, Maneeton N, Likhitsathian S, Suttajit S, Narkpongphun A, Srisurapanont M, Woottiluk P, "Comparative efficacy, acceptability, and tolerability of lisdexamfetamine in child and adolescent ADHD: a meta-analysis of randomized, controlled trials", Drug design, development and therapy, 2013 Jan .
- Najib J, Wimer D, Zeng J, Lam KW, Romanyak N, Paige Morgan E, Thadavila A, "Review of Lisdexamfetamine Dimesylate in Adults With Attention-Deficit/Hyperactivity Disorder", Journal of central nervous system disease, 2017 Aug .
- Maneeton N, Maneeton B, Suttajit S, Reungyos J, Srisurapanont M, Martin SD, "Exploratory meta-analysis on lisdexamfetamine versus placebo in adult ADHD", Drug design, development and therapy, 2017 Jan .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Maneeton B, Maneeton N, Likhitsathian S, Suttajit S, Narkpongphun A, Srisurapanont M, Woottiluk P, "Comparative efficacy, acceptability, and tolerability of lisdexamfetamine in child and adolescent ADHD: a meta-analysis of randomized, controlled trials", Drug design, development and therapy, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on eszopiclone and lisdexamfetamine dimesylate (the active ingredients of Eszopiclone and Vyvanse, respectively), and Eszopiclone and Vyvanse (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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