Etomidate and Methylprednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Etomidate (etomidate) and Methylprednisolone (methylprednisolone). Common drug interactions include gingival erosion among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Etomidate and Methylprednisolone. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Etomidate?

Etomidate has active ingredients of etomidate. eHealthMe is studying from 2,496 Etomidate users. Check the latest studies of Etomidate.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.



On Jul, 30, 2026

53 people who take Etomidate and Methylprednisolone together, and have interactions are studied.

Etomidate and Methylprednisolone drug interactions.

What are the common drug interactions of Etomidate and Methylprednisolone, by gender? *:

female:

  1. Gingival erosion (gum ulcer)
  2. Gingival swelling (gums swelling)
  3. Hyperthyroidism (over activity of the thyroid gland)
  4. Infection
  5. Jaw disorder (jaw disease)
  6. Jaw fracture
  7. Lymphoma (cancer that begins in immune system cells)
  8. Mass
  9. Mastocytosis (an excessive number of apparently normal mast cells in the skin and, occasionally, in other organs)
  10. Metastasis (spreadable cancer to other organ from origin)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Pyrexia (fever)
  4. Renal failure (kidney dysfunction)
  5. Respiratory distress (difficulty in breathing)
  6. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  7. Acute respiratory failure
  8. Anaphylactic reaction (serious allergic reaction)
  9. Anxiety
  10. Bacteraemia (presence of bacteria in the blood)

What are the common drug interactions of Etomidate and Methylprednisolone, by age (0-1 to 60+)? *:

0-1:

  1. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  2. Hyperpyrexia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions- infectious)

2-9:

n/a

10-19:

n/a

20-29:

  1. Bradycardia (abnormally slow heart action)
  2. Blood magnesium decreased
  3. Blood pressure decreased
  4. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  5. Electrocardiogram st segment depression
  6. Haemoglobin decreased
  7. Haemorrhage (bleeding)
  8. Heart rate increased
  9. Hyperkalaemia (damage to or disease of the kidney)
  10. Hypokinesia (decreased bodily movement)

30-39:

  1. Aortic valve disease
  2. Cardiac failure congestive
  3. Cardiac valve disease (heart valve disease)
  4. Cerebral artery embolism (sudden blocking of an artery by a clot or foreign material)
  5. Cerebral infarction (less blood supply to brain resulting tissue damage)
  6. Coma (state of unconsciousness lasting more than six hours)
  7. Kidney transplant rejection
  8. Leukaemoid reaction (elevated white blood cell count, or leukocytosis, that is a physiological response to stress or infection)
  9. Post procedural complication
  10. Postictal paralysis

40-49:

  1. Gastroenteritis (inflammation of stomach and intestine)
  2. Lymphadenopathy (disease or enlargement of lymph nodes)
  3. Pharyngeal stenosis (narrowing of the pharyngeal airway)
  4. Pyrexia (fever)
  5. Upper respiratory tract infection

50-59:

  1. Abscess neck (neck abscesses)
  2. Acute circulatory failure (shock)
  3. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  4. Alanine aminotransferase increased
  5. Anal abscess
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Aplasia (defective development or congenital absence of an organ or tissue)
  9. Blood creatine phosphokinase increased
  10. Blood lactate dehydrogenase increased

60+:

  1. Diplopia (double vision)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Exophthalmos (bulging or protruding eyeball)
  4. Fibrocystic breast disease (a condition causing breast pain, cysts, and noncancerous breast lumps, affects many women)
  5. Gingival erosion (gum ulcer)
  6. Gingival swelling (gums swelling)
  7. Hyperthyroidism (over activity of the thyroid gland)
  8. Infection
  9. Jaw disorder (jaw disease)
  10. Jaw fracture

What are the existing conditions these people have? *

  1. Urticaria Pigmentosa (skin disease that produces patches of darker skin (lesions) and very bad itching): 8 people, 15.09%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 15.09%
  3. Pain: 5 people, 9.43%
  4. Stress And Anxiety: 3 people, 5.66%
  5. Pneumonia: 3 people, 5.66%
  6. Infection: 3 people, 5.66%
  7. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Etomidate and Methylprednisolone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Etomidate and Methylprednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Etomidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methylprednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Etomidate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylprednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on etomidate and methylprednisolone (the active ingredients of Etomidate and Methylprednisolone, respectively), and Etomidate and Methylprednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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