Euthyrox and Progesterone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Euthyrox (levothyroxine sodium) and Progesterone (progesterone). Common drug interactions include hydrops foetalis among females and blood thyroid stimulating hormone decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Euthyrox and Progesterone. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Euthyrox?

Euthyrox has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 8,740 Euthyrox users. Check the latest studies of Euthyrox.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

On Jul, 20, 2026

40 people who take Euthyrox and Progesterone together, and have interactions are studied.

Euthyrox and Progesterone drug interactions.

What are the common drug interactions of Euthyrox and Progesterone, by gender? *:

female:

Hydrops foetalis (fetus characterized by an accumulation of fluid)
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Retroplacental haematoma (blood collection entirely behind the placenta)
Fatigue (feeling of tiredness)
Breast enlargement
Dizziness
Histamine intolerance
Lichen sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain)
Maternal exposure during pregnancy (use of substance during pregnancy)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)

male:

Blood thyroid stimulating hormone decreased
Depression
Suicidal ideation
Cystitis (inflammation of the wall of the bladder)
Dizziness
Rash

What are the common drug interactions of Euthyrox and Progesterone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Haemorrhage in pregnancy (bleeding in pregnancy)
Hydrops foetalis (fetus characterized by an accumulation of fluid)
Oligohydramnios (a condition in pregnancy characterized by a deficiency of amniotic fluid)
Retroplacental haematoma (blood collection entirely behind the placenta)
Abortion spontaneous (naturally occurring miscarriage)
Gastroschisis (a hole in the abdominal wall)
Maternal exposure during pregnancy (use of substance during pregnancy)
Subdural hygroma (subdural collection of cerebrospinal fluid (csf), without blood)

30-39:

Maternal exposure during pregnancy (use of substance during pregnancy)
Dizziness
Drug eruption (adverse drug reaction of the skin)
Enterococcal infection
Escherichia infection (bacterial infection by escherichia coli)
Gestational diabetes (diabetes in pregnancy)
Live birth
Nausea (feeling of having an urge to vomit)
Premature delivery
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

40-49:

Breast enlargement
Fatigue (feeling of tiredness)
Histamine intolerance
Lichen sclerosus (a skin disorder that causes the skin to become thin, whitened, wrinkled, and can cause itching and pain)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Oestradiol increased
Performance status decreased
Dizziness
Cardiovascular disorder (heart diseases)
Hot flush (sudden feelings of heat)

50-59:

Peripheral swelling
Swelling face
Syncope (loss of consciousness with an inability to maintain postural tone)
Alopecia (absence of hair from areas of the body)
Fatigue (feeling of tiredness)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Headache (pain in head)
Heart rate increased
Insomnia (sleeplessness)
Palpitations (feelings or sensations that your heart is pounding or racing)

60+:

Cystitis (inflammation of the wall of the bladder)
Dizziness
Rash

What are the existing conditions these people have? *

Haemorrhage In Pregnancy (bleeding in pregnancy): 15 people, 37.50%
Tension Headache: 14 people, 35.00%
Foetal Exposure During Pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect): 4 people, 10.00%
Stress And Anxiety: 2 people, 5.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 5.00%
Escherichia Infection (bacterial infection by escherichia coli): 2 people, 5.00%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 5.00%
Enterococcal Infection: 2 people, 5.00%
Depression: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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