Evening primrose and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evening primrose (evening primrose oil) and Humalog (insulin lispro recombinant). Common drug interactions include blood glucose increased among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Evening primrose and Humalog. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Evening primrose?

Evening primrose has active ingredients of evening primrose oil. It is often used in breast pain. eHealthMe is studying from 1,794 Evening primrose users. Check the latest studies of Evening primrose.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

On Jul, 25, 2026

26 people who take Evening primrose and Humalog together, and have interactions are studied.

Evening primrose and Humalog drug interactions.

What are the common drug interactions of Evening Primrose and Humalog, by gender? *:

female:

Blood glucose increased
Malaise (a feeling of general discomfort or uneasiness)
Arthralgia (joint pain)
Back disorder
Blood glucose decreased
Fall
Gait disturbance
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Osteomyelitis (infection of bone)
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

male:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Colitis ulcerative (inflammation of colon with ulcer)
Sleep terror (felling of terror in sleep)
Spinal column stenosis (narrowing of spinal column)
Vitreous floaters (spots before the eyes)
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Diabetic foot
Diabetic foot infection
Drug ineffective
Eye haemorrhage (bleeding in the eye)

What are the common drug interactions of Evening Primrose and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Infection
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Nephrolithiasis (calculi in the kidneys)
Abdominal pain upper

30-39:

Osteomyelitis (infection of bone)
Diabetic foot infection
Graft complication
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Colitis ulcerative (inflammation of colon with ulcer)
Drug ineffective

40-49:

n/a

50-59:

Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Diabetic foot
Diabetic foot infection
Fluid overload (too much fluid in the blood)
Hyperglycaemia (high blood sugar)
Malaise (a feeling of general discomfort or uneasiness)
Oropharyngeal pain
Pallor
Renal failure (kidney dysfunction)

60+:

Blood glucose increased
Arthralgia (joint pain)
Therapeutic response increased (high preventive response)
Chest pain
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Blindness transient (sudden loss of vision)
Hyperhidrosis (abnormally increased sweating)
Tremor (trembling or shaking movements in one or more parts of your body)
Blood pressure increased
Conjunctival haemorrhage (bleeding underneath the conjunctiva)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 9 people, 34.62%
Asthma: 4 people, 15.38%
Type 2 Diabetes: 3 people, 11.54%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 7.69%
High Blood Pressure: 2 people, 7.69%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.69%
Chest Pain: 2 people, 7.69%
Bipolar Disorder (mood disorder): 2 people, 7.69%
Acne (skin problems that cause pimples): 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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