Everolimus and Pemetrexed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Everolimus (everolimus) and Pemetrexed (pemetrexed). Common drug interactions include pulmonary haemorrhage among females and ascites among males.
The phase IV clinical study analyzes what interactions people have when they take Everolimus and Pemetrexed. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Everolimus?
Everolimus has active ingredients of everolimus. eHealthMe is studying from 16,228 Everolimus users. Check the latest studies of Everolimus.
What is Pemetrexed?
Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.
19 people who take Everolimus and Pemetrexed together, and have interactions are studied.

What are the common drug interactions of Everolimus and Pemetrexed, by gender? *:
female:
- Pulmonary haemorrhage (acute bleeding from the lung)
- Pulmonary embolism (blockage of the main artery of the lung)
- Disease progression
- Pulmonary mass
- Malignant neoplasm progression (cancer tumour came back)
- Metastases to lung (cancer spreads to lung)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
male:
- Ascites (accumulation of fluid in the abdominal cavity)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Hepatotoxicity (chemical-driven liver damage)
- Erysipelas (bacterial skin infection)
- Lymphoedema (localized fluid retention and tissue swelling)
- Malignant neoplasm progression (cancer tumour came back)
- Oedema peripheral (superficial swelling)
- Pleural effusion (water on the lungs)
- Pneumonia
- Renal failure (kidney dysfunction)
What are the common drug interactions of Everolimus and Pemetrexed, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Pulmonary haemorrhage (acute bleeding from the lung)
- Pulmonary embolism (blockage of the main artery of the lung)
- Pulmonary mass
40-49:
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
50-59:
n/a
60+:
- Malignant neoplasm progression (cancer tumour came back)
- Ascites (accumulation of fluid in the abdominal cavity)
- Disease progression
- Metastases to lung (cancer spreads to lung)
- Pulmonary embolism (blockage of the main artery of the lung)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Erysipelas (bacterial skin infection)
- Lymphoedema (localized fluid retention and tissue swelling)
- Oedema peripheral (superficial swelling)
- Pleural effusion (water on the lungs)
What are the existing conditions these people have? *
- Neoplasm Malignant (cancer tumour): 4 people, 21.05%
- Metastatic Bronchial Carcinoma (spread of cancer to bronchi tumour): 4 people, 21.05%
- Thymoma (a tumour originating from the epithelial cells of the thymus): 3 people, 15.79%
- Breast Cancer: 2 people, 10.53%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 1 person, 5.26%
- Metastatic Neoplasm (spreadable cancer tumour): 1 person, 5.26%
- Lung Adenocarcinoma Stage Iii (the cancer has spread to nearby tissue or too far away lymph nodes): 1 person, 5.26%
- Bronchial Carcinoma (lung cancer): 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Everolimus and Pemetrexed?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Everolimus (16,228 reports)
- Pemetrexed (17,491 reports)
Browse all drug interactions of Everolimus and Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Everolimus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pemetrexed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Everolimus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pemetrexed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
- Gota V, Kavathiya K, Doshi K, Gurjar M, Damodaran SE, Noronha V, Joshi A, Prabhash K, "High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy", Cancer management and research, 2017 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on everolimus and pemetrexed (the active ingredients of Everolimus and Pemetrexed, respectively), and Everolimus and Pemetrexed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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