Evista and Adalat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evista (raloxifene hydrochloride) and Adalat (nifedipine). Common drug interactions include headache among females.

The phase IV clinical study analyzes what interactions people have when they take Evista and Adalat. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Evista?

Evista has active ingredients of raloxifene hydrochloride. It is often used in osteoporosis. eHealthMe is studying from 25,891 Evista users. Check the latest studies of Evista.

What is Adalat?

Adalat has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 20,940 Adalat users. Check the latest studies of Adalat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

93 people who take Evista and Adalat together, and have interactions are studied.

Evista and Adalat drug interactions.

What are the common drug interactions of Evista and Adalat, by gender? *:

female:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Altered state of consciousness (altered state of mind)
  4. Angina pectoris (chest pain due to ischemia of the heart muscle)
  5. Fatigue (feeling of tiredness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Osteitis (a general term for inflammation of bone)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Depressed mood
  10. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)

male:

n/a

What are the common drug interactions of Evista and Adalat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Gastric mucosa erythema (reddened mucosa of stomach)
  2. Gastritis (inflammation of stomach)
  3. Headache (pain in head)
  4. Oedema (fluid collection in tissue)
  5. Foot fracture
  6. Furuncle (infection of the hair follicle)

50-59:

n/a

60+:

  1. Arthralgia (joint pain)
  2. Decreased appetite
  3. Fatigue (feeling of tiredness)
  4. Nausea (feeling of having an urge to vomit)
  5. Osteitis (a general term for inflammation of bone)
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Depressed mood
  8. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
  9. Gastric ulcer (stomach ulcer)
  10. Gastroenteritis (inflammation of stomach and intestine)

What are the existing conditions these people have? *

  1. Cerebral Infarction (less blood supply to brain resulting tissue damage): 8 people, 8.60%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 6 people, 6.45%
  3. Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 6.45%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 5.38%
  5. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

Do you take Evista and Adalat?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Evista and Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Evista:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adalat:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Evista and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adalat and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on raloxifene hydrochloride and nifedipine (the active ingredients of Evista and Adalat, respectively), and Evista and Adalat (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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