Evoxac and Motrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Evoxac (cevimeline hydrochloride) and Motrin (ibuprofen). Common drug interactions include weight decreased among females.

The phase IV clinical study analyzes what interactions people have when they take Evoxac and Motrin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

What is Motrin?

Motrin has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 38,332 Motrin users. Check the latest studies of Motrin.

On Jul, 14, 2026

20 people who take Evoxac and Motrin together, and have interactions are studied.

What are the common drug interactions of Evoxac and Motrin, by gender? *:

female:

Weight decreased
Depression
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Heart rate increased
Hypersensitivity
Type 2 diabetes mellitus
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Attention deficit/hyperactivity disorder
Gastric polyps (abnormal growth of stomach tissue projecting from a mucous membrane)
Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)

male:

n/a

What are the common drug interactions of Evoxac and Motrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chills (felling of cold)
Diarrhoea
Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Night sweats (sweating in night)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Drug hypersensitivity
Hospitalisation
Kidney infection
Type 2 diabetes mellitus
Weight decreased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Drug effect decreased
Heart rate increased
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Adrenal cyst (cysts of the adrenal gland)

60+:

Myelodysplastic syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged)
Acute lymphocytic leukaemia (cancer of the white blood cells)
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 40.00%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 40.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 30.00%
Abdominal Pain Upper: 4 people, 20.00%
Thyroid Diseases: 3 people, 15.00%
High Blood Cholesterol: 3 people, 15.00%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 3 people, 15.00%
Gastric Disorder (disease of stomach): 2 people, 10.00%
High Blood Pressure: 2 people, 10.00%
Depression: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Evoxac and Motrin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously