Evoxac and Sulfamethoxazole drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Evoxac (cevimeline hydrochloride) and Sulfamethoxazole (sulfamethoxazole). Common drug interactions include cardiac failure congestive among females and bronchitis among males.
The phase IV clinical study analyzes what interactions people have when they take Evoxac and Sulfamethoxazole. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Evoxac?
Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.
What is Sulfamethoxazole?
Sulfamethoxazole has active ingredients of sulfamethoxazole. It is often used in urinary tract infection. eHealthMe is studying from 13,360 Sulfamethoxazole users. Check the latest studies of Sulfamethoxazole.
17 people who take Evoxac and Sulfamethoxazole together, and have interactions are studied.

What are the common drug interactions of Evoxac and Sulfamethoxazole, by gender? *:
female:
- Cardiac failure congestive
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Arrhythmia (irregular heartbeat)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Sudden death
- Death
- Hyperkalaemia (damage to or disease of the kidney)
male:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Sinusitis (inflammation of sinus)
- Cataract (clouding of the lens inside the eye)
- Intervertebral disc protrusion (spinal disc protrusion)
- Muscle spasms (muscle contraction)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Nephrosclerosis (hardening of the kidney due to renovascular disease)
- Plasma cell myeloma (cancer that begins in plasma cells)
- Asthma
- Chlamydial infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis)
What are the common drug interactions of Evoxac and Sulfamethoxazole, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Renal failure (kidney dysfunction)
- Chronic kidney disease
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Death
- Hyperkalaemia (damage to or disease of the kidney)
- Nephrosclerosis (hardening of the kidney due to renovascular disease)
- Renal injury (kidney injury)
- Septic shock (shock due to blood infection)
60+:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Sinusitis (inflammation of sinus)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Renal failure (kidney dysfunction)
- Sudden death
- Cataract (clouding of the lens inside the eye)
- Muscle spasms (muscle contraction)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
- Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 52.94%
- High Blood Cholesterol: 9 people, 52.94%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 52.94%
- Inflammation: 6 people, 35.29%
- Stress And Anxiety: 5 people, 29.41%
- Depression: 5 people, 29.41%
- Dry Mouth: 5 people, 29.41%
- Immunodeficiency Common Variable: 4 people, 23.53%
- Type 2 Diabetes: 4 people, 23.53%
- Infection: 4 people, 23.53%
* Approximation only. Some reports may have incomplete information.
Do you take Evoxac and Sulfamethoxazole?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Evoxac (2,028 reports)
- Sulfamethoxazole (13,360 reports)
Browse all drug interactions of Evoxac and Sulfamethoxazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Evoxac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sulfamethoxazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Evoxac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sulfamethoxazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cevimeline hydrochloride and sulfamethoxazole (the active ingredients of Evoxac and Sulfamethoxazole, respectively), and Evoxac and Sulfamethoxazole (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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