Exalgo and Potassium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exalgo (hydromorphone hydrochloride) and Potassium (potassium). Common drug interactions include depression among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Exalgo and Potassium. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Exalgo?

Exalgo has active ingredients of hydromorphone hydrochloride. It is often used in chronic pain. eHealthMe is studying from 9,847 Exalgo users. Check the latest studies of Exalgo.

What is Potassium?

Potassium has active ingredients of potassium. It is often used in hypokalemia. eHealthMe is studying from 59,148 Potassium users. Check the latest studies of Potassium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

23 people who take Exalgo and Potassium together, and have interactions are studied.

Exalgo and Potassium drug interactions.

What are the common drug interactions of Exalgo and Potassium, by gender? *:

female:

  1. Depression
  2. Tibia fracture (fracture of lower leg bone)
  3. Tooth extraction
  4. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  5. Trigger finger
  6. Vitamin d deficiency
  7. Arthralgia (joint pain)
  8. Discomfort
  9. Dysuria (painful or difficult urination)
  10. Headache (pain in head)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Nephropathy (damage to or disease of a kidney)
  4. Renal injury (kidney injury)
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  7. Diarrhoea
  8. Hyperchlorhydria (gastric acid levels are higher in stomach)
  9. Intestinal obstruction
  10. Rebound effect (take-back effect)

What are the common drug interactions of Exalgo and Potassium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Cystitis (inflammation of the wall of the bladder)
  3. Dehydration (dryness resulting from the removal of water)
  4. Depression
  5. Dysuria (painful or difficult urination)
  6. Emotional disorder
  7. Infrequent bowel movements
  8. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  9. Nausea (feeling of having an urge to vomit)
  10. Pyelonephritis (inflammation of kidney caused by bacteria)

40-49:

  1. Abdominal pain
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Back pain
  5. Butterfly rash
  6. Collagen disorder (infection and weakness of collagen)
  7. Cough
  8. Depression
  9. Discomfort
  10. Dry skin

50-59:

  1. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  2. Drug level increased
  3. Intestinal obstruction
  4. Loss of consciousness

60+:

  1. Abdominal pain upper
  2. Ankle fracture
  3. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  4. Dehydration (dryness resulting from the removal of water)
  5. Depression
  6. Discomfort
  7. Fall
  8. Fibula fracture
  9. Foot fracture
  10. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the existing conditions these people have? *

  1. Pain: 16 people, 69.57%
  2. Restless Leg Syndrome (a powerful urge to move your legs): 13 people, 56.52%
  3. Muscle Spasms (muscle contraction): 13 people, 56.52%
  4. Depression: 11 people, 47.83%
  5. Chest Pain: 11 people, 47.83%
  6. Indigestion: 10 people, 43.48%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 43.48%
  8. Nausea (feeling of having an urge to vomit): 10 people, 43.48%
  9. Swelling: 10 people, 43.48%
  10. Infection: 10 people, 43.48%

* Approximation only. Some reports may have incomplete information.

Do you take Exalgo and Potassium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exalgo and Potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exalgo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exalgo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Potassium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydromorphone hydrochloride and potassium (the active ingredients of Exalgo and Potassium, respectively), and Exalgo and Potassium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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