Excedrin and Cod liver oil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Excedrin (acetaminophen; aspirin; caffeine) and Cod liver oil (cod liver oil). Common drug interactions include blood pressure increased among females and sleep apnoea syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Excedrin and Cod liver oil. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Cod liver oil?

Cod liver oil has active ingredients of cod liver oil. It is often used in joint pain. eHealthMe is studying from 3,636 Cod liver oil users. Check the latest studies of Cod liver oil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

17 people who take Excedrin and Cod liver oil together, and have interactions are studied.

Excedrin and Cod liver oil drug interactions.

What are the common drug interactions of Excedrin and Cod Liver Oil, by gender? *:

female:

  1. Blood pressure increased
  2. Feeling cold
  3. Lethargy (tiredness)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  6. Mood swings (an extreme or rapid change in mood)
  7. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

  1. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Excedrin and Cod Liver Oil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Agitation (state of anxiety or nervous excitement)
  2. Anxiety
  3. Dizziness
  4. Dyspnoea (difficult or laboured respiration)
  5. Palpitations (feelings or sensations that your heart is pounding or racing)

40-49:

n/a

50-59:

  1. Back pain
  2. Burning sensation
  3. Chills (felling of cold)
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Erythema (redness of the skin)
  7. Feeling hot
  8. Flushing (the warm, red condition of human skin)
  9. Gait disturbance
  10. Grip strength decreased

60+:

  1. Abdominal pain upper
  2. Asthenia (weakness)
  3. Anxiety
  4. Body temperature decreased
  5. Chills (felling of cold)
  6. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  7. Depressed mood
  8. Drug intolerance (drug sensitivity)
  9. Hordeolum (small collection of pus (abscess) on the eyelid)
  10. Hypoaesthesia (reduced sense of touch or sensation)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 70.59%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 17.65%
  3. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 17.65%
  4. Pain: 2 people, 11.76%
  5. Sleep Disorder: 1 person, 5.88%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  7. Migraine (headache): 1 person, 5.88%
  8. Insomnia (sleeplessness): 1 person, 5.88%
  9. Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 5.88%
  10. Gait Disturbance: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and Cod liver oil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Excedrin and Cod liver oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cod liver oil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cod liver oil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine and cod liver oil (the active ingredients of Excedrin and Cod liver oil, respectively), and Excedrin and Cod liver oil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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