Excedrin and Nabumetone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Excedrin (acetaminophen; aspirin; caffeine) and Nabumetone (nabumetone). Common drug interactions include hallucination among females.

The phase IV clinical study analyzes what interactions people have when they take Excedrin and Nabumetone. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Nabumetone?

Nabumetone has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 9,554 Nabumetone users. Check the latest studies of Nabumetone.

On Jul, 19, 2026

30 people who take Excedrin and Nabumetone together, and have interactions are studied.

Excedrin and Nabumetone drug interactions.

What are the common drug interactions of Excedrin and Nabumetone, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Thrombosis (formation of a blood clot inside a blood vessel)
Abdominal pain
Appendicitis (inflammation of the appendix)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cellulitis (infection under the skin)
Cholecystitis chronic (long lasting infection of gallbladder)
Dehydration (dryness resulting from the removal of water)
Gallbladder disorder
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

male:

n/a

What are the common drug interactions of Excedrin and Nabumetone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Appendicitis (inflammation of the appendix)
Cholecystitis chronic (long lasting infection of gallbladder)
Coagulopathy (blood's ability to clot is impaired)
Gallbladder disorder
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Muscle spasms (muscle contraction)
Muscle twitching
Pain in jaw

20-29:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)

30-39:

n/a

40-49:

Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Vomiting
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Oesophageal candidiasis (fungal infection of oesophagus)
Adverse drug reaction
Anxiety
Depression
Dizziness
Fibromyalgia (a long-term condition which causes pain all over the body)

50-59:

Visual impairment
Vomiting
Cellulitis (infection under the skin)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Gallbladder operation
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)
Pain in extremity
Skin burning sensation
Suicidal ideation

60+:

Coagulopathy (blood's ability to clot is impaired)
Haemorrhagic stroke (stroke caused by the rupture of a blood vessel in the brain)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 30.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 16.67%
Drowsiness: 5 people, 16.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 16.67%
High Blood Cholesterol: 3 people, 10.00%
Sick Sinus Syndrome (a collection of heart rhythm disorders): 2 people, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.67%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.67%
Muscle Disorder (muscle disease): 2 people, 6.67%
Migraine (headache): 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and Nabumetone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously