Excedrin and Nurtec odt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Excedrin (acetaminophen; aspirin; caffeine) and Nurtec odt (rimegepant sulfate). Common drug interactions include fall among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Excedrin and Nurtec odt. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

What is Nurtec odt?

Nurtec odt has active ingredients of rimegepant sulfate. eHealthMe is studying from 9,221 Nurtec odt users. Check the latest studies of Nurtec odt.



On Jul, 07, 2026

82 people who take Excedrin and Nurtec odt together, and have interactions are studied.

Excedrin and Nurtec odt drug interactions.

What are the common drug interactions of Excedrin and Nurtec Odt, by gender? *:

female:

  1. Fall
  2. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  3. Viral infection
  4. Blood iron decreased
  5. Oropharyngeal pain
  6. Urinary tract infection
  7. Wheezing (a high-pitched whistling sound made while you breath)
  8. Cyst (a closed sac)
  9. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  10. Loss of consciousness

male:

  1. Dizziness
  2. Nausea (feeling of having an urge to vomit)
  3. Performance status decreased
  4. Pituitary tumour benign
  5. Drug ineffective
  6. Eye irritation
  7. Eye pain
  8. Injection site pain

What are the common drug interactions of Excedrin and Nurtec Odt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pruritus (severe itching of the skin)
  2. Cough
  3. Hypersensitivity

30-39:

  1. Fall
  2. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  3. Viral infection
  4. Blood iron decreased
  5. Urinary tract infection
  6. Wheezing (a high-pitched whistling sound made while you breath)
  7. Cyst (a closed sac)
  8. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  9. Loss of consciousness
  10. Vulval cellulitis (inflammation of skin around vagina)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Drug ineffective
  3. Adverse drug reaction
  4. Arthralgia (joint pain)
  5. Blood pressure increased
  6. Chest discomfort
  7. Chronic kidney disease
  8. Delirium (wild excitement)
  9. Ear infection
  10. Ear pain

50-59:

  1. Drug ineffective
  2. Dizziness
  3. Nausea (feeling of having an urge to vomit)
  4. Performance status decreased

60+:

  1. Depressed mood
  2. Drug ineffective
  3. Burning sensation
  4. Chest discomfort
  5. Discomfort
  6. Dry skin
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  8. Oral disorder (mouth disease)
  9. Overdose
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

  1. Migraine (headache): 52 people, 63.41%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 8.54%

* Approximation only. Some reports may have incomplete information.

Do you take Excedrin and Nurtec odt?

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- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Excedrin and Nurtec odt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Excedrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nurtec odt:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Excedrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nurtec odt and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; aspirin; caffeine and rimegepant sulfate (the active ingredients of Excedrin and Nurtec odt, respectively), and Excedrin and Nurtec odt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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