Exforge hct and Zolpidem drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge hct (amlodipine; hydrochlorothiazide; valsartan) and Zolpidem (zolpidem tartrate). Common drug interactions include pneumonia among females and presyncope among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge hct and Zolpidem. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge hct?

Exforge hct has active ingredients of amlodipine; hydrochlorothiazide; valsartan. It is often used in high blood pressure. eHealthMe is studying from 4,095 Exforge hct users. Check the latest studies of Exforge hct.

What is Zolpidem?

Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 28, 2026

20 people who take Exforge hct and Zolpidem together, and have interactions are studied.

Exforge hct and Zolpidem drug interactions.

What are the common drug interactions of Exforge Hct and Zolpidem, by gender? *:

female:

  1. Pneumonia
  2. Fatigue (feeling of tiredness)
  3. Constipation
  4. Cough
  5. Pleural effusion (water on the lungs)
  6. Acute hepatic failure
  7. Cystitis (inflammation of the wall of the bladder)
  8. Decreased appetite
  9. Idiopathic pulmonary fibrosis (chronic lung disease)
  10. Increased bronchial secretion

male:

  1. Presyncope
  2. Cardiac disorder
  3. Heart rate increased
  4. Hypersensitivity
  5. Muscle spasms (muscle contraction)
  6. Oedema peripheral (superficial swelling)
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

What are the common drug interactions of Exforge Hct and Zolpidem, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Acute respiratory failure
  2. Blood cholesterol increased
  3. Blood pressure decreased
  4. Blood pressure systolic increased
  5. Bradycardia (abnormally slow heart action)
  6. Cough
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Rhinorrhoea (watery mucus discharge from the nose)
  9. Septic shock (shock due to blood infection)
  10. Shunt infection

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Increased bronchial secretion
  4. Nephritis (inflammation of the nephrons in the kidneys)
  5. Oedema peripheral (superficial swelling)
  6. Pleural effusion (water on the lungs)
  7. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  8. Acute hepatic failure
  9. Weight increased
  10. Cystitis noninfective (non-infectious inflammation of the wall of the bladder)

What are the existing conditions these people have? *

  1. Sleep Disorder: 6 people, 30.00%
  2. Idiopathic Pulmonary Fibrosis (chronic lung disease): 6 people, 30.00%
  3. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 30.00%
  4. Pulmonary Thrombosis (scarring in the lungs): 2 people, 10.00%
  5. Neuropathy Peripheral (surface nerve damage): 2 people, 10.00%
  6. High Blood Cholesterol: 2 people, 10.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 10.00%
  8. Depression: 2 people, 10.00%
  9. Back Pain: 2 people, 10.00%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge hct and Zolpidem?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge hct and Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge hct:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zolpidem:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge hct and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zolpidem and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine; hydrochlorothiazide; valsartan and zolpidem tartrate (the active ingredients of Exforge hct and Zolpidem, respectively), and Exforge hct and Zolpidem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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