Exforge and Colace drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Colace (docusate ). Common drug interactions include diarrhoea among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Colace. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Colace?

Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 41,841 Colace users. Check the latest studies of Colace.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

28 people who take Exforge and Colace together, and have interactions are studied.

What are the common drug interactions of Exforge and Colace, by gender? *:

female:

Diarrhoea
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Abdominal pain
Flushing (the warm, red condition of human skin)
Insomnia (sleeplessness)
Abdominal discomfort
Arthralgia (joint pain)
Atrioventricular block (heart block)
B-cell lymphoma (blood cancer affecting b cells)
Blood pressure fluctuation

male:

Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Metastatic malignant melanoma (spreadable cancer tumour of melanine)
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Vision blurred
Vomiting
Weight decreased
Chest pain
Haematochezia (passage of stools containing blood)

What are the common drug interactions of Exforge and Colace, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain
Nausea (feeling of having an urge to vomit)
Balance disorder
Cyst (a closed sac)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Dizziness
Fatigue (feeling of tiredness)
Lymphoedema (localized fluid retention and tissue swelling)
Malignant neoplasm progression (cancer tumour came back)

60+:

Chest pain
Haematochezia (passage of stools containing blood)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)
Atrioventricular block (heart block)
Back pain
Body temperature increased
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Confusional state

What are the existing conditions these people have? *

High Blood Pressure: 11 people, 39.29%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 21.43%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 17.86%
Multiple Myeloma (cancer of the plasma cells): 4 people, 14.29%
Erection Problems: 4 people, 14.29%
Pain In Extremity: 2 people, 7.14%
Pain: 2 people, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 7.14%
Joint Pain: 2 people, 7.14%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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