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Exforge and Colecalciferol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Colecalciferol (cholecalciferol). Common drug interactions include general physical health deterioration among females and angina unstable among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Colecalciferol. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Colecalciferol?

Colecalciferol has active ingredients of cholecalciferol. eHealthMe is studying from 21,262 Colecalciferol users. Check the latest studies of Colecalciferol.

On Jul, 16, 2026

20 people who take Exforge and Colecalciferol together, and have interactions are studied.

Exforge and Colecalciferol drug interactions.

What are the common drug interactions of Exforge and Colecalciferol, by gender? *:

female:

  1. General physical health deterioration (weak health status)
  2. Haematemesis (vomiting of blood)
  3. Hypotension (abnormally low blood pressure)
  4. Asthma
  5. Abdominal pain
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Anxiety
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  9. Asthenia (weakness)
  10. Back pain

male:

  1. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Blood creatinine increased
  4. Blood thyroid stimulating hormone decreased
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Colitis (inflammation of colon)
  7. Decreased appetite
  8. Diarrhoea
  9. Dizziness
  10. Erythema (redness of the skin)

What are the common drug interactions of Exforge and Colecalciferol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Asthenia (weakness)
  4. Bone density decreased
  5. Depression
  6. Emotional distress
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Pain
  9. Renal impairment (severely reduced kidney function)
  10. Sensory loss (senses loss)

50-59:

  1. Abdominal pain
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Asthma
  4. Colitis ulcerative (inflammation of colon with ulcer)
  5. Fatigue (feeling of tiredness)
  6. Glaucoma (increased fluid pressure in the eye with vision loss)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Mouth ulceration (mouth ulcers)
  9. Obesity (having too much body fat)
  10. Oral herpes (viral infection of mouth)

60+:

  1. General physical health deterioration (weak health status)
  2. Haematemesis (vomiting of blood)
  3. Blood thyroid stimulating hormone decreased
  4. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  5. Chronic kidney disease
  6. Colitis (inflammation of colon)
  7. Decreased appetite
  8. Diarrhoea
  9. Dizziness
  10. Emotional distress

What are the existing conditions these people have? *

  1. Hiv Infection: 3 people, 15.00%
  2. Asthma: 2 people, 10.00%
  3. High Blood Pressure: 2 people, 10.00%
  4. Non-Alcoholic Steatohepatitis (liver inflammation caused by a build up of fat in the liver): 2 people, 10.00%
  5. Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 2 people, 10.00%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
  7. Back Pain: 1 person, 5.00%
  8. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 5.00%
  9. Bladder Cancer: 1 person, 5.00%
  10. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and Colecalciferol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge and Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Colecalciferol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Colecalciferol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan and cholecalciferol (the active ingredients of Exforge and Colecalciferol, respectively), and Exforge and Colecalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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