Exforge and Melphalan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Exforge (amlodipine besylate; valsartan) and Melphalan (melphalan). Common drug interactions include somnolence among females and basal cell carcinoma among males.

The phase IV clinical study analyzes what interactions people have when they take Exforge and Melphalan. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Exforge?

Exforge has active ingredients of amlodipine besylate; valsartan. It is often used in high blood pressure. eHealthMe is studying from 13,350 Exforge users. Check the latest studies of Exforge.

What is Melphalan?

Melphalan has active ingredients of melphalan. eHealthMe is studying from 20,052 Melphalan users. Check the latest studies of Melphalan.



On Jul, 24, 2026

13 people who take Exforge and Melphalan together, and have interactions are studied.

Exforge and Melphalan drug interactions.

What are the common drug interactions of Exforge and Melphalan, by gender? *:

female:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Anaemia (lack of blood)
  3. Herpes zoster
  4. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  5. Infective myositis (infection of skeletal muscle)
  6. Neutropenia (an abnormally low number of neutrophils)
  7. Constipation
  8. Delirium (wild excitement)
  9. Fatigue (feeling of tiredness)
  10. Hypoaesthesia (reduced sense of touch or sensation)

male:

  1. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  2. Malignant melanoma (skin cancer rises from melancytes)
  3. Muscular weakness (muscle weakness)
  4. Fungal infection
  5. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)

What are the common drug interactions of Exforge and Melphalan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Diarrhoea
  2. Urinary tract infection
  3. Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
  4. Infective myositis (infection of skeletal muscle)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Fungal infection
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Constipation
  10. Delirium (wild excitement)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 13 people, 100.00%
  2. High Blood Pressure: 9 people, 69.23%
  3. Diabetes: 3 people, 23.08%
  4. Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 3 people, 23.08%
  5. Fever: 3 people, 23.08%
  6. Hypokalemia (low potassium): 3 people, 23.08%
  7. Weight Loss: 2 people, 15.38%
  8. Insomnia (sleeplessness): 2 people, 15.38%
  9. Nausea And Vomiting: 2 people, 15.38%
  10. Diarrhea: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

Do you take Exforge and Melphalan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Exforge and Melphalan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Exforge:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Melphalan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Exforge and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melphalan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate; valsartan and melphalan (the active ingredients of Exforge and Melphalan, respectively), and Exforge and Melphalan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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